ID A0A3B6IVY0_WHEAT Unreviewed; 847 AA.
AC A0A3B6IVY0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7051290.1, ECO:0000313|EnsemblPlants:TraesCS4B02G358800.1};
GN ORFNames=CFC21_059542 {ECO:0000313|EMBL:KAF7051290.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4B02G358800.1};
RN [1] {ECO:0000313|EMBL:KAF7051290.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7051290.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4B02G358800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4B02G358800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4B02G358800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7051290.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7051290.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the RBOH (TC 5.B.1.3) family.
CC {ECO:0000256|ARBA:ARBA00007975}.
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DR EMBL; CM022221; KAF7051290.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6IVY0; -.
DR SMR; A0A3B6IVY0; -.
DR STRING; 4565.A0A3B6IVY0; -.
DR PaxDb; 4565-Traes_4BL_25A23A7EC-1; -.
DR EnsemblPlants; TraesCS4B02G358800.1; TraesCS4B02G358800.1; TraesCS4B02G358800.
DR Gramene; TraesCAD_scaffold_004928_01G000700.1; TraesCAD_scaffold_004928_01G000700.1; TraesCAD_scaffold_004928_01G000700.
DR Gramene; TraesCLE_scaffold_017440_01G000300.1; TraesCLE_scaffold_017440_01G000300.1; TraesCLE_scaffold_017440_01G000300.
DR Gramene; TraesCS4B02G358800.1; TraesCS4B02G358800.1; TraesCS4B02G358800.
DR Gramene; TraesCS4B03G0930800.1; TraesCS4B03G0930800.1.CDS; TraesCS4B03G0930800.
DR Gramene; TraesKAR4B01G0436620.1; cds.TraesKAR4B01G0436620.1; TraesKAR4B01G0436620.
DR Gramene; TraesPAR_scaffold_015303_01G000100.1; TraesPAR_scaffold_015303_01G000100.1; TraesPAR_scaffold_015303_01G000100.
DR Gramene; TraesROB_scaffold_011797_01G000600.1; TraesROB_scaffold_011797_01G000600.1; TraesROB_scaffold_011797_01G000600.
DR Gramene; TraesWEE_scaffold_038397_01G000200.1; TraesWEE_scaffold_038397_01G000200.1; TraesWEE_scaffold_038397_01G000200.
DR OMA; RSYWAVH; -.
DR OrthoDB; 367877at2759; -.
DR Proteomes; UP000019116; Chromosome 4B.
DR Proteomes; UP000815260; Chromosome 4B.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016174; F:NAD(P)H oxidase H2O2-forming activity; IBA:GO_Central.
DR GO; GO:0004601; F:peroxidase activity; IEA:UniProtKB-KW.
DR CDD; cd00051; EFh; 1.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR000778; Cyt_b245_heavy_chain.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR013623; NADPH_Ox.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972:SF141; MEMBRANE-BOUND NADPH OXIDASE; 1.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR Pfam; PF08414; NADPH_Ox; 1.
DR PRINTS; PR00466; GP91PHOX.
DR SFLD; SFLDG01169; NADPH_oxidase_subgroup_(NOX); 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 298..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 511..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 171..206
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 529..657
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 95331 MW; BC671C457A945848 CRC64;
MADIEAGGKP ATESDTATLI PNSGNLEGSS RATKTCRFKD NDELVEITLD VQRDSASVQA
VRPVAAEAAV AAARKRYDRS KSTAAVALKG LQFVTAKVGT DGWAAVEKRF NHLQVDGVLL
RSRFGKCIGM DGSDEFAVQM FDALARKRGI VKEVLTKPEL KEFWEQLSDQ GFDNRLQTFI
DMVDKNADGR ITVEEVKEII ALSASANKLS KIKERADEYA ALIMEELDPK NLGYIELESL
ESLLLQTPSE AVARSTITHS SKLSKALSMR LAPSKDTSPI RHYWLQFTFF VEENWKRIWV
AALWISICIA LFIWKFIQYR NRAVFNIMGY CVATAKGAAE TLKFNMALVL FPVCRNTITW
IRSKTKIGAV VPFNDNINFH KVIAAGVAVG VVLHAGAHLT CDFPLLLHAS DAKYEPMKPF
FGETRPPNYW WFVKGTAGWT GIVMVVLMSI SFVLAQPWFR RNKLKDSNPL KKMTGFNAFW
FTHHLFAIVY ALLIVHGTSL YLTKEWYKKT TWMYIAYPVF LYSCERIVRL FRRHDSVKIQ
KVAVYPGNVL ALYMSKPPGF KYRSGQYIFI NCGAVSPYEW HPFSVTSAPG DNYLSVHIRT
RGDWTSRLRT VFSEACRPPT EGESGLLRAD LSVGITDSNA RFPKLMIDGP YGAPAQDYRE
YDVLLLIGLG IGATPLISIV KDVLNHIQRG ESVGGTEPDG SGKAKKKPFM TKRAYSYWVT
REEGSFEWFR GVMNEVAEKD KDGVIELHNH CSSVYQEGDA RSALIVMLQE LNHAKKGVDI
LSGTSVKTHF ARPNWRSVFK RIAVNHENQR VGVFYCGEPV LVAQLRQLSA DFTHNTNTKF
DFHKENF
//
