ID A0A3B6JIX1_WHEAT Unreviewed; 891 AA.
AC A0A3B6JIX1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=GTP diphosphokinase {ECO:0000256|ARBA:ARBA00013251};
DE EC=2.7.6.5 {ECO:0000256|ARBA:ARBA00013251};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4D02G169500.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS4D02G169500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4D02G169500.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4D02G169500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RelA/SpoT family.
CC {ECO:0000256|ARBA:ARBA00007476}.
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DR AlphaFoldDB; A0A3B6JIX1; -.
DR SMR; A0A3B6JIX1; -.
DR STRING; 4565.A0A3B6JIX1; -.
DR PaxDb; 4565-Traes_4DL_0C31AFCF9-1; -.
DR EnsemblPlants; TraesCS4D02G169500.1; TraesCS4D02G169500.1; TraesCS4D02G169500.
DR Gramene; TraesCAD_scaffold_009814_01G000300.1; TraesCAD_scaffold_009814_01G000300.1; TraesCAD_scaffold_009814_01G000300.
DR Gramene; TraesCLE_scaffold_027634_01G000100.1; TraesCLE_scaffold_027634_01G000100.1; TraesCLE_scaffold_027634_01G000100.
DR Gramene; TraesCS4D02G169500.1; TraesCS4D02G169500.1; TraesCS4D02G169500.
DR Gramene; TraesCS4D03G0420700.2; TraesCS4D03G0420700.2.CDS; TraesCS4D03G0420700.
DR Gramene; TraesKAR4D01G0212920.1; cds.TraesKAR4D01G0212920.1; TraesKAR4D01G0212920.
DR Gramene; TraesPAR_scaffold_038767_01G000100.1; TraesPAR_scaffold_038767_01G000100.1; TraesPAR_scaffold_038767_01G000100.
DR Gramene; TraesROB_scaffold_032867_01G000100.1; TraesROB_scaffold_032867_01G000100.1; TraesROB_scaffold_032867_01G000100.
DR Gramene; TraesWEE_scaffold_109997_01G000100.1; TraesWEE_scaffold_109997_01G000100.1; TraesWEE_scaffold_109997_01G000100.
DR OrthoDB; 1396at2759; -.
DR Proteomes; UP000019116; Chromosome 4D.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0008728; F:GTP diphosphokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd02116; ACT; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR CDD; cd01668; TGS_RSH; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR InterPro; IPR004095; TGS.
DR InterPro; IPR012676; TGS-like.
DR InterPro; IPR033655; TGS_RelA/SpoT.
DR PANTHER; PTHR43061; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR43061:SF1; GTP DIPHOSPHOKINASE RSH1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR Pfam; PF02824; TGS; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81271; TGS-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51880; TGS; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT DOMAIN 183..290
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT DOMAIN 573..636
FT /note="TGS"
FT /evidence="ECO:0000259|PROSITE:PS51880"
SQ SEQUENCE 891 AA; 98914 MW; CA02B0167B81A8B4 CRC64;
MQPPTAALSA SSLECASSCR ALWKGGGGAG RPYECSVLSC AWNAPRALTG ALASTTQCSS
CSHAEAVGGG RRRGRPRQSN NNTLLHITWA EDINKGKLGH GSSASFVSSV KKIRYWSTPV
KSMWRVSCYS SGPFDLVSPE TLWESLRPAI SYLQPEELNF VHDALKLAYE AHNGQKRRSG
EPFIIHPVEV ARILGEHELD WESIAAGLLH DTVEDTDMVT FETIQNEFGA TVSRIVEGET
KVSKLGKLQC KNEGSSKQDV KAEDLRQMFL AMTEEVRVII VKLADRLHNM RTLTHMPQHK
QYAIAMETLQ VFAPLAKLLG MYQIKSELEY LSFMYMNPGD FAELRKRVDD IFKAHEQELE
EANKILKQKI AEDQFLDLVS VETEVRSVCK ELYSIYKTAL KSKSSLNEVN QVAQLRIIIK
PKSCNGVGPL CTGQQICYHV LGLVHGIWTP IPQAVKDYIA TPKPNGYQSL HTTVIPFLNE
SMFHLEVQIR TEDMDLIAER GIAAHYSGRG VVSGPVRPGI SSGRNLDGKV ICLNNTGFAL
RIGWLNAIRE WQEEFVGNMS SREFVDTITR DLLGSRVFVF TPKGEIKNLP KGATVIDYAY
LIHTEIGNKM VAAKVNGNLV SPIHALANAE VVEIITYDKL SSKYAFQRHQ QWLQHAKTRS
ARHKIMKFLR EQAALSAAEI TADAVNNFVA DLEDESDSEQ LIPTTQNEDY KFNWQKILSS
NKLSFVNKNS DGFLPVNNIH TPKINGKHNK TVKELGIKIN GSTVRGDSST EFMRPGVPAY
KEVFASLDNW KCGKISSWHN TEGNSIQWLC IVCVDRKGMM AEVTSALTAC GITICSCVAE
RDNRRGMGVL LFHFEGTDEN VVSACSSVEM ILGVLGWSAG CSYNPLGVLE C
//
