ID A0A3B6JPC8_WHEAT Unreviewed; 749 AA.
AC A0A3B6JPC8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=VWFA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_063428 {ECO:0000313|EMBL:KAF7055964.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4D02G339300.1};
RN [1] {ECO:0000313|EMBL:KAF7055964.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7055964.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4D02G339300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4D02G339300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4D02G339300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7055964.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7055964.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022222; KAF7055964.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6JPC8; -.
DR STRING; 4565.A0A3B6JPC8; -.
DR PaxDb; 4565-Traes_4DL_1501A18E2-1; -.
DR EnsemblPlants; TraesCS4D02G339300.1; TraesCS4D02G339300.1; TraesCS4D02G339300.
DR Gramene; TraesCAD_scaffold_012171_01G000800.1; TraesCAD_scaffold_012171_01G000800.1; TraesCAD_scaffold_012171_01G000800.
DR Gramene; TraesCLE_scaffold_013248_01G000800.1; TraesCLE_scaffold_013248_01G000800.1; TraesCLE_scaffold_013248_01G000800.
DR Gramene; TraesCS4D02G339300.1; TraesCS4D02G339300.1; TraesCS4D02G339300.
DR Gramene; TraesCS4D03G0787800.1; TraesCS4D03G0787800.1.CDS; TraesCS4D03G0787800.
DR Gramene; TraesPAR_scaffold_015360_01G000800.1; TraesPAR_scaffold_015360_01G000800.1; TraesPAR_scaffold_015360_01G000800.
DR Gramene; TraesROB_scaffold_057333_01G000300.1; TraesROB_scaffold_057333_01G000300.1; TraesROB_scaffold_057333_01G000300.
DR Gramene; TraesWEE_scaffold_007997_01G000300.1; TraesWEE_scaffold_007997_01G000300.1; TraesWEE_scaffold_007997_01G000300.
DR OMA; HTEYSAV; -.
DR Proteomes; UP000019116; Chromosome 4D.
DR Proteomes; UP000815260; Chromosome 4D.
DR CDD; cd01466; vWA_C3HC4_type; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR032838; Vwaint_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF150; VWFA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00092; VWA; 1.
DR Pfam; PF14624; Vwaint; 1.
DR Pfam; PF17123; zf-RING_11; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 24..68
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 248..444
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 97..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..136
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..171
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 749 AA; 79795 MW; 33DD795004B199F7 CRC64;
MEIPDQQPAV AVAEMEAPDQ ENPCAICLGG MAAGGGQATF TAECSHTFHF NCISASVAHG
HLVCPLCNAR WRELPFLRPT APVPQPPTLP RLGRPVPMHG VQPPSEPTAS PPLMHGGMPP
FPAQAPPPPR GHIMQHHQPP PPNVHVVQHH QPPPPVHTVQ HHQPPPPEPT VVFDDDEQVE
PASRPPADST PAAASNGAVV VNTHAEYSAV ARDSSSDNFA VLVHVKAPAM ADTVAAGSDK
PPPRAPLDLV TVLDVSGSMS GHKLALLKQA MRFVIDNLGP NDRLSVVSFS SEARRLTRLT
RMSDAGKALA VSAVESLAAR GGTNIAEGLR TAAKVLDERR HRNAVSSVVL LSDGQDTYTM
MRRRGPSGVQ ANNYEELVPP SFARTGADGE WSAPIHTFGF GNDHDAAAMH VIAEATGGTF
SFIENEAVIQ DAFAQCIGGL LSVVVQEARI AVACVHPGVR VVSVKSGRYE SRVDEDGCAA
SVRVGELYAD EERRFLLFLT VPRVEATDGD TTALARVVFS YRNAASGAEV SVTAEDTVVA
RPEHAPSASE RSVEVERERV RVEAAEDIAA ARAAAERGEH QEAVEILDNR QRALEQSEAA
GDGDPMIVAL GAELQEMRGR VSNRQSYMRS GRAYMLAGMS AHQQQRATSR QMLEPEEQQT
SMMARNSGVR RMIRRGVGSS GGGYMAAAAP VAEASNEATM SYATPAMRAM LLRSREARGA
SAEQGQQEEQ QPMAGKDDAG SSGPKDVNQ
//
