ID A0A3B6JRA2_WHEAT Unreviewed; 367 AA.
AC A0A3B6JRA2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein {ECO:0000259|Pfam:PF01212};
GN ORFNames=CFC21_063503 {ECO:0000313|EMBL:KAF7056047.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS4D02G346900.1};
RN [1] {ECO:0000313|EMBL:KAF7056047.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7056047.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS4D02G346900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS4D02G346900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS4D02G346900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7056047.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7056047.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the threonine aldolase family.
CC {ECO:0000256|ARBA:ARBA00006966}.
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DR EMBL; CM022222; KAF7056047.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6JRA2; -.
DR SMR; A0A3B6JRA2; -.
DR STRING; 4565.A0A3B6JRA2; -.
DR EnsemblPlants; TraesCS4D02G346900.1; TraesCS4D02G346900.1; TraesCS4D02G346900.
DR Gramene; TraesCAD_scaffold_085289_01G000200.1; TraesCAD_scaffold_085289_01G000200.1; TraesCAD_scaffold_085289_01G000200.
DR Gramene; TraesCLE_scaffold_110700_01G000100.1; TraesCLE_scaffold_110700_01G000100.1; TraesCLE_scaffold_110700_01G000100.
DR Gramene; TraesCS4D02G346900.1; TraesCS4D02G346900.1; TraesCS4D02G346900.
DR Gramene; TraesCS4D03G0805300.1; TraesCS4D03G0805300.1.CDS; TraesCS4D03G0805300.
DR Gramene; TraesKAR4D01G0363220.1; cds.TraesKAR4D01G0363220.1; TraesKAR4D01G0363220.
DR Gramene; TraesKAR4D01G0363220.2; cds.TraesKAR4D01G0363220.2; TraesKAR4D01G0363220.
DR Gramene; TraesPAR_scaffold_184926_01G000100.1; TraesPAR_scaffold_184926_01G000100.1; TraesPAR_scaffold_184926_01G000100.
DR Gramene; TraesROB_scaffold_091858_01G000100.1; TraesROB_scaffold_091858_01G000100.1; TraesROB_scaffold_091858_01G000100.
DR Gramene; TraesWEE_scaffold_097069_01G000100.1; TraesWEE_scaffold_097069_01G000100.1; TraesWEE_scaffold_097069_01G000100.
DR OMA; IERCKHY; -.
DR OrthoDB; 178754at2759; -.
DR Proteomes; UP000019116; Chromosome 4D.
DR Proteomes; UP000815260; Chromosome 4D.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0008732; F:L-allo-threonine aldolase activity; IBA:GO_Central.
DR GO; GO:0006545; P:glycine biosynthetic process; IBA:GO_Central.
DR GO; GO:0006567; P:threonine catabolic process; IBA:GO_Central.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR023603; Low_specificity_L-TA-like.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; NF041359; GntG_guanitoxin; 1.
DR PANTHER; PTHR48097:SF11; AROMATIC AMINO ACID BETA-ELIMINATING LYASE_THREONINE ALDOLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR PIRSF; PIRSF017617; Thr_aldolase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 7..294
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
FT MOD_RES 207
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR017617-1"
SQ SEQUENCE 367 AA; 38965 MW; 9A9D7E93A6B84753 CRC64;
MATKVVDLRS DTVTKPSEAM RAAMAAADVD DDVLGADPTA CRFEAEMARI MGKEAALFVP
SGTMANLISV LAHCDARGSE VILGDDSHIH VYEHGGISTL GGVHPRTVPN NPDGTMDVDR
IVAAIRSTDG ALYYPTTRLI CLENTHGNSG GKCLTVEYTD KVGEVAKAHG LKLHIDGARI
FNASVALGVP VDRLVRAADS VSVCLSKGIG APVGSVIVGS KAFIQKAKIL RKTLGGGMRQ
VGVLCAAAEV GVRDTLGKLA DDHRKAKVLA DGLKKIKHFT VDLTSVETNM VFFDMADPRI
TPAKLCQALK QRSVLAMPTS SKSVRFVVHY QISDGDIQYT LKCIEEAVEE MLACDAKSER
CSTNGTS
//
