ID A0A3B6KFK7_WHEAT Unreviewed; 385 AA.
AC A0A3B6KFK7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=PABS domain-containing protein {ECO:0000259|PROSITE:PS51006};
GN ORFNames=CFC21_065493 {ECO:0000313|EMBL:KAF7058429.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5A02G172600.1};
RN [1] {ECO:0000313|EMBL:KAF7058429.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7058429.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5A02G172600.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5A02G172600.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5A02G172600.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7058429.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7058429.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867, ECO:0000256|RuleBase:RU003836}.
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DR EMBL; CM022223; KAF7058429.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6KFK7; -.
DR SMR; A0A3B6KFK7; -.
DR STRING; 4565.A0A3B6KFK7; -.
DR PaxDb; 4565-Traes_5AL_9873DB737-1; -.
DR EnsemblPlants; TraesCS5A02G172600.1; TraesCS5A02G172600.1; TraesCS5A02G172600.
DR Gramene; TraesCAD_scaffold_063213_01G000100.1; TraesCAD_scaffold_063213_01G000100.1; TraesCAD_scaffold_063213_01G000100.
DR Gramene; TraesCLE_scaffold_006200_01G000400.1; TraesCLE_scaffold_006200_01G000400.1; TraesCLE_scaffold_006200_01G000400.
DR Gramene; TraesCS5A02G172600.1; TraesCS5A02G172600.1; TraesCS5A02G172600.
DR Gramene; TraesCS5A03G0462900.1; TraesCS5A03G0462900.1.CDS; TraesCS5A03G0462900.
DR Gramene; TraesKAR5A01G0221100.1; cds.TraesKAR5A01G0221100.1; TraesKAR5A01G0221100.
DR Gramene; TraesPAR_scaffold_089572_01G000100.1; TraesPAR_scaffold_089572_01G000100.1; TraesPAR_scaffold_089572_01G000100.
DR Gramene; TraesROB_scaffold_043883_01G000500.1; TraesROB_scaffold_043883_01G000500.1; TraesROB_scaffold_043883_01G000500.
DR Gramene; TraesWEE_scaffold_088517_01G000100.1; TraesWEE_scaffold_088517_01G000100.1; TraesWEE_scaffold_088517_01G000100.
DR OMA; EATCHET; -.
DR OrthoDB; 1126121at2759; -.
DR Proteomes; UP000019116; Chromosome 5A.
DR Proteomes; UP000815260; Chromosome 5A.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0004766; F:spermidine synthase activity; IBA:GO_Central.
DR GO; GO:0008295; P:spermidine biosynthetic process; IBA:GO_Central.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.30.140.10; Spermidine synthase, tetramerisation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_00198; Spermidine_synth; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR030373; PABS_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR001045; Spermi_synthase.
DR InterPro; IPR030668; Spermi_synthase_euk.
DR InterPro; IPR035246; Spermidine_synt_N.
DR InterPro; IPR037163; Spermidine_synt_N_sf.
DR NCBIfam; TIGR00417; speE; 1.
DR PANTHER; PTHR11558; SPERMIDINE/SPERMINE SYNTHASE; 1.
DR PANTHER; PTHR11558:SF25; SPERMINE SYNTHASE; 1.
DR Pfam; PF17284; Spermine_synt_N; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR PIRSF; PIRSF000502; Spermidine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01330; PABS_1; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Polyamine biosynthesis {ECO:0000256|PROSITE-ProRule:PRU00354};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 52..303
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 222
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 385 AA; 41945 MW; 5E296C30732759F7 CRC64;
MEGGDARNGL TGTSQTTGSG VESPAKPLPP CCVKARAAAP ESEAKCHATV VSGWFTETRS
RCGKASKLQY YNNPMWPGET HSLKVEKILY QGKSPYQEVL IFESLTYGKV LVLDGIVQLT
DKDECAYQEM ITHLPLCSIP SPKKVLVIGG GDGGVLREIA RHGSVESIDI CEIDQLVIDV
CKDFFPDLSV GFKDPRVRLH VGDAVEFLRN SPEGTYDAII VDSSDPIGPA QELVEKPFFE
TIARALRPGG VLCNQAESMW LHTHLIQDML SICCETFKGS VHYAWASVPT YPSGAIGFLL
CSKEGRPVNF LAPINPIEKI EGAMTAGRDI RFYNTEMHRA AFVLPTFAKR ELEAYGGSTR
GAQQEEKSAE PAKVAIVPHS EILTA
//
