ID   A0A3B6KGU0_WHEAT        Unreviewed;       791 AA.
AC   A0A3B6KGU0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0000259|SMART:SM00487};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5A02G163800.3};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCS5A02G163800.3}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCS5A02G163800.3};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCS5A02G163800.3}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00000600};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:13066;
CC         Evidence={ECO:0000256|ARBA:ARBA00000600};
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DR   AlphaFoldDB; A0A3B6KGU0; -.
DR   EnsemblPlants; TraesCS5A02G163800.3; TraesCS5A02G163800.3; TraesCS5A02G163800.
DR   Gramene; TraesCS5A02G163800.3; TraesCS5A02G163800.3; TraesCS5A02G163800.
DR   Gramene; TraesCS5A03G0445200.3; TraesCS5A03G0445200.3.CDS; TraesCS5A03G0445200.
DR   Proteomes; UP000019116; Chromosome 5A.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd18044; DEXXQc_SMUBP2; 1.
DR   Gene3D; 2.40.30.270; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43788:SF3; P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN; 1.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT   DOMAIN          501..753
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|SMART:SM00487"
FT   REGION          61..109
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..83
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..109
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   791 AA;  86869 MW;  8761A6C910F1F503 CRC64;
     MAMKQAKYQF LFSSSATVLH LRRSELKLLS SPSFLSSTSS APISSLHQGH LRLVPSASPT
     EQVLLPDDSH STTPNGTSSN GNRNKGRRRS RRKSKETAKE EKERVPSAEE VSIRMAEAYE
     SGDPLGRKEL GRCVMQWLKL GMCSMASTFA STEVQNDGAA FSLDGGSSEG TLEFMILAQP
     YLAATPMPKG HEALCLKAST HYPTLFDHFQ RELREVLLKH QNQGLISDWR STESWMLLKK
     SAKSAQHRQG ARKPKAPAMH NLLGISLDKT RLMQTKIEDF VKKMSDLLNI ERDAELEFTQ
     EELNATPTMD SAAKQPLKPV EYLVSHGQAE QEQCDTVCNL NVISTSTGLG GLRLVLFRVE
     GTHKLPPSTL SPGDMVCVRT CNSQGEVGTS CVQGFIHNLG EDGCSITVSL KSRPGDPTFS
     KFSGKSVRID RIQALADGLT YERNCEALIL LQRKGLQKTN ACIGVVATLF GDKEDMTMLE
     QSNLTDWGAS AIQDNGLLGK YKYDFDASQS QAIALGLNKK RPVLVIQGPP GTGKTGLLSY
     LIDCAVRQGE RVLVTAPSNA AVDNMVEKLS GTGLNIVRVG NPARISPSVS SRSLGELVKR
     RLAKFTQEFQ RKKSNLRKDL KQCIQDDSLA AGIRQLLKKL GKNFRKKENE IIKEVLSNAD
     VVLSTNIGAA DPLIKEIGFF DLVIIDEAGQ AIEPSCWIPI LRGKRCILAG DQHQLAPVIL
     SREAMQGGLG MSLLERASSL HDELLTTKLT MQYRMHESIA NWASNEMYFG LLKSSSSVAS
     RLLFDYPSIQ V
//