ID A0A3B6LFG2_WHEAT Unreviewed; 378 AA.
AC A0A3B6LFG2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=BHLH domain-containing protein {ECO:0000259|PROSITE:PS50888};
GN ORFNames=CFC21_069564 {ECO:0000313|EMBL:KAF7063031.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5B02G013000.2};
RN [1] {ECO:0000313|EMBL:KAF7063031.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7063031.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5B02G013000.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5B02G013000.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5B02G013000.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7063031.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7063031.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the bHLH protein family.
CC {ECO:0000256|ARBA:ARBA00005510}.
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DR EMBL; CM022224; KAF7063031.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6LFG2; -.
DR SMR; A0A3B6LFG2; -.
DR STRING; 4565.A0A3B6LFG2; -.
DR EnsemblPlants; TraesCS5B02G013000.2; TraesCS5B02G013000.2; TraesCS5B02G013000.
DR Gramene; TraesCS5B02G013000.2; TraesCS5B02G013000.2; TraesCS5B02G013000.
DR Gramene; TraesCS5B03G0028100.1; TraesCS5B03G0028100.1.CDS; TraesCS5B03G0028100.
DR Gramene; TraesRN5B0100029500.1; TraesRN5B0100029500.1; TraesRN5B0100029500.
DR Proteomes; UP000019116; Chromosome 5B.
DR Proteomes; UP000815260; Chromosome 5B.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR45959; BHLH TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR45959:SF57; OS12G0632600 PROTEIN; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 173..222
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 21..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 135..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..85
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..171
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 40354 MW; B5041F0ACA39EE35 CRC64;
MDDFMQWAMN TLDQQQYHAA AAAAAPPVYG GAAGSSSGGS SAGAAFPSLQ ALRESTAAGA
GVRDLRVQVD HHQPSSWSTS SGDSPGAAMD HDAAAAGPGW SPHTARARTR ATSSSRPMSW
NFSAAAASAQ LPADIDISPR PAPAPRGHST PAAGRRSGAS AQGTTAGPSA SPGPVQDHII
AERRRREKIN QRFIELSTVI PNLKKMDKAT ILGDAVKYVR ELQEKVKTME DDDSAAAAAT
TTTTIRSAVL VSKKIKADDE DDDDEDAGES SHGGLPEIEV RVSGEKTVLV RIHCKNARGL
LVRVLAEVEE LRLAITHTSV MPFPADTAII TITAKVLYSM HVNSIIARKL CDRIRRCDNP
KWDILIDLWK NKRPLYML
//
