ID A0A3B6LFJ3_WHEAT Unreviewed; 290 AA.
AC A0A3B6LFJ3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=cysteine dioxygenase {ECO:0000256|ARBA:ARBA00013133};
DE EC=1.13.11.20 {ECO:0000256|ARBA:ARBA00013133};
GN ORFNames=CFC21_069674 {ECO:0000313|EMBL:KAF7063148.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5B02G023400.1};
RN [1] {ECO:0000313|EMBL:KAF7063148.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7063148.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5B02G023400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5B02G023400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5B02G023400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7063148.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7063148.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-cysteine + O2 = 3-sulfino-L-alanine + H(+);
CC Xref=Rhea:RHEA:20441, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
CC ChEBI:CHEBI:35235, ChEBI:CHEBI:61085; EC=1.13.11.20;
CC Evidence={ECO:0000256|ARBA:ARBA00024284};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20442;
CC Evidence={ECO:0000256|ARBA:ARBA00024284};
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
CC -!- SIMILARITY: Belongs to the cysteine dioxygenase family.
CC {ECO:0000256|ARBA:ARBA00006622}.
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DR EMBL; CM022224; KAF7063148.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6LFJ3; -.
DR SMR; A0A3B6LFJ3; -.
DR STRING; 4565.A0A3B6LFJ3; -.
DR PaxDb; 4565-Traes_5BS_55D3CCDBC-1; -.
DR EnsemblPlants; TraesCS5B02G023400.1; TraesCS5B02G023400.1; TraesCS5B02G023400.
DR Gramene; TraesCAD_scaffold_007660_01G000200.1; TraesCAD_scaffold_007660_01G000200.1; TraesCAD_scaffold_007660_01G000200.
DR Gramene; TraesCS5B02G023400.1; TraesCS5B02G023400.1; TraesCS5B02G023400.
DR Gramene; TraesCS5B03G0054300.1; TraesCS5B03G0054300.1.CDS; TraesCS5B03G0054300.
DR Gramene; TraesWEE_scaffold_026552_01G000200.1; TraesWEE_scaffold_026552_01G000200.1; TraesWEE_scaffold_026552_01G000200.
DR OMA; FFRTIDN; -.
DR Proteomes; UP000019116; Chromosome 5B.
DR Proteomes; UP000815260; Chromosome 5B.
DR GO; GO:0017172; F:cysteine dioxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0070483; P:detection of hypoxia; IEA:UniProt.
DR CDD; cd20289; cupin_ADO; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR012864; PCO/ADO.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR PANTHER; PTHR22966:SF63; CYSTEINE DIOXYGENASE; 1.
DR PANTHER; PTHR22966; UNCHARACTERIZED; 1.
DR Pfam; PF07847; PCO_ADO; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT REGION 21..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 31963 MW; F1CCA00327882B02 CRC64;
MGADAAGLDV ARAKRRRVLA AKTRGGRPRQ ARRRAQPQPP TALQRLFRAC RAVFRGPGTV
PAPHEVALLR AMLDGMRPED VGLSPGMRFF RTIDNAAPGN PTITHTTIYE SDNFSMVILY
LPQNAVIPLH NHPGMTVFSK LLIGSMHIKS YDSTDPDDLA VLDLRLAELV VDDLFTAPCD
TSVLYPTAGG NMHRFTAIAP CAILDILGPP YSIEERDCTY YADVPYSSHH LRTLTSNEQE
GRRLAWLKEV EQLKPQLKQD DVRIVCRVTI AAKLAASAVS IGFSLCMMSQ
//
