ID A0A3B6LKH3_WHEAT Unreviewed; 981 AA.
AC A0A3B6LKH3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_071147 {ECO:0000313|EMBL:KAF7064947.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5B02G161000.1};
RN [1] {ECO:0000313|EMBL:KAF7064947.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7064947.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5B02G161000.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5B02G161000.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5B02G161000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7064947.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7064947.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022224; KAF7064947.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6LKH3; -.
DR SMR; A0A3B6LKH3; -.
DR STRING; 4565.A0A3B6LKH3; -.
DR EnsemblPlants; TraesCS5B02G161000.1; TraesCS5B02G161000.1; TraesCS5B02G161000.
DR Gramene; TraesCAD_scaffold_039459_01G000100.1; TraesCAD_scaffold_039459_01G000100.1; TraesCAD_scaffold_039459_01G000100.
DR Gramene; TraesCLE_scaffold_091689_01G000200.1; TraesCLE_scaffold_091689_01G000200.1; TraesCLE_scaffold_091689_01G000200.
DR Gramene; TraesCS5B02G161000.1; TraesCS5B02G161000.1; TraesCS5B02G161000.
DR Gramene; TraesCS5B03G0437900.2; TraesCS5B03G0437900.2.CDS; TraesCS5B03G0437900.
DR Gramene; TraesPAR_scaffold_017973_01G000100.1; TraesPAR_scaffold_017973_01G000100.1; TraesPAR_scaffold_017973_01G000100.
DR Gramene; TraesROB_scaffold_098551_01G000200.1; TraesROB_scaffold_098551_01G000200.1; TraesROB_scaffold_098551_01G000200.
DR Gramene; TraesWEE_scaffold_039091_01G000200.1; TraesWEE_scaffold_039091_01G000200.1; TraesWEE_scaffold_039091_01G000200.
DR OMA; WITRCAF; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000019116; Chromosome 5B.
DR Proteomes; UP000815260; Chromosome 5B.
DR GO; GO:0043139; F:5'-3' DNA helicase activity; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18044; DEXXQc_SMUBP2; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 2.40.30.270; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF3; P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASES SUPERFAMILY PROTEIN; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 505..722
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 730..934
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT REGION 63..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 981 AA; 107610 MW; BE92AED8D04D5EDD CRC64;
MAMKHAKYQF LFSSSATVLH LRRRELKLLS SPSFLSSSSS APISSLQQGH LRLVPSAGPT
EQVLLPADSH STTPNGTSSN GNRNMARRRS RRKSKETAKE EKECVPSAEE VSIRIAEAYE
SGDPLGRKEL GRCVMQWLKL GMCSMASAFA STEVQNDGAA FSLDGELSEG SLEFMILAQP
YLAATPMPKG HEALCLKAST HYPTLFDHFQ RELREVLLKH QNQGLISDWR STESWMLLKK
LAKSAQHRQG ARKPKPPTMH NLLGISLDKT RLMQTKIEDF VKKMSDLLNI ERDAELEFTQ
EELNATPTMD SAAKQSLKPV EYLVSHGQAE QEQCDTVCNL NVISTSTGLG GLRLVLFRVE
GTHKLPPSTL SPGDMVCVRT CNNQGEVGTS CVQGFIHNLG EDGCSITVSL KSRPGDPTFS
KFSGKSVRID RIQALADGLT YERNCEALIL LQRKGLQKTN ACIGVVATLF GDKEDMTMLE
QNNLTDWGES AIQDNGLLGK SKYDFDASQS QAITLGLNKK RPVLVIQGPP GTGKTGLLSY
LIDCAVRQGE RVLVTAPSNA AVDNMVEKLS GTGLNIVRVG NPARISPSVS SRSLGELVKM
RLAKFTQEFQ RKKSNLRKDL KQCIQDDSLA AGIRQLLKKL GKNFRKKENE IIKEVLSNAD
VVLSTNIGAA DPLIKEIGFF DLVIIDEAGQ AIEPSCWIPI LRGKRCILAG DQNQLAPVIL
SREAMQGGLG MSLLERASSL HDELLTTKLT MQYRMHESIA NWASNEMYFG LLKSSPSVAS
RLLVDYPSIQ ETWITRCALL LLDTRMPYGS LNIDCEEHLD LAGTGSFYNS GEADIVAQHV
VNLVLCGVSP TSIAVQSPYI AQVQLLRDRL EEYPEALGVE VSTIDSFQGR EADAVVISMV
RSNSLGAVGF LGDNRRMNVA ITRARRHVAL VCDSSTICNN EFLARLLRHI RQHGQVRHVE
PGSYGGDYGL GFSPPALPSI S
//
