ID A0A3B6LSN3_WHEAT Unreviewed; 475 AA.
AC A0A3B6LSN3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=MBD domain-containing protein {ECO:0000259|PROSITE:PS50982};
GN ORFNames=CFC21_073355 {ECO:0000313|EMBL:KAF7067464.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5B02G374200.1};
RN [1] {ECO:0000313|EMBL:KAF7067464.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7067464.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5B02G374200.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5B02G374200.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5B02G374200.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7067464.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7067464.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CM022224; KAF7067464.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6LSN3; -.
DR SMR; A0A3B6LSN3; -.
DR STRING; 4565.A0A3B6LSN3; -.
DR PaxDb; 4565-Traes_5BL_8F2E81CCA-1; -.
DR EnsemblPlants; TraesCS5B02G374200.1; TraesCS5B02G374200.1; TraesCS5B02G374200.
DR Gramene; TraesCS5B02G374200.1; TraesCS5B02G374200.1; TraesCS5B02G374200.
DR Gramene; TraesCS5B03G0940500.2; TraesCS5B03G0940500.2.CDS; TraesCS5B03G0940500.
DR OMA; WKKRFTP; -.
DR OrthoDB; 622866at2759; -.
DR Proteomes; UP000019116; Chromosome 5B.
DR Proteomes; UP000815260; Chromosome 5B.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR039622; MBD10/11.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR PANTHER; PTHR33729; METHYL-CPG BINDING DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR PANTHER; PTHR33729:SF6; METHYL-CPG-BINDING DOMAIN-CONTAINING PROTEIN 10; 1.
DR Pfam; PF01429; MBD; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS50982; MBD; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 21..88
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..151
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..259
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..289
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..324
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 475 AA; 50907 MW; 4D0FA651B2A56061 CRC64;
MASEGEHAAA AGEQTPLKKA GEAEQGEELQ APSGWTKKLN PTRGGKFEVA FVAPTGEEVK
TKRALTTYLK AHPGGPALSE FVWATGNTPR RSSRLSAKPK ATESPEDEKP SRRSGKSKAT
ESPEDEKPAK RGRPSSSKKG KKGKQEDAED AEAESGDHAD AEEAKGTEVE MKDAEEAKVT
DLDLEMKEAD NAQEEKKEEE AGGSVGEKKE ADTVAQEEKK EADTVAQEEK KEADPVAQEE
KKEADTLAQE EKKEADTVAE EEKEEADTVA QEEMKDAPVA DAPEKTEEVE GEAAESEVAP
VETEMPDPVT ENKENEKPAE FEEVPVEFEM SDLVSENKEN EKPAESEEVP VEFEMSAPVL
EEHKEDEKPA EYEVAPVEGE KTENGLAVES TVSPPATSEE KKVEADSTIN PATPPPAEVK
ADAPAAEAAK AAENPADNTA HKDDQGNAGT TGEQSTGNVD NNGQIHPGVS TVRCI
//
