ID A0A3B6LX15_WHEAT Unreviewed; 226 AA.
AC A0A3B6LX15;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=CFC21_075076 {ECO:0000313|EMBL:KAF7069446.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5B02G546700.1};
RN [1] {ECO:0000313|EMBL:KAF7069446.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7069446.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5B02G546700.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5B02G546700.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5B02G546700.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7069446.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7069446.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022224; KAF7069446.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6LX15; -.
DR SMR; A0A3B6LX15; -.
DR STRING; 4565.A0A3B6LX15; -.
DR EnsemblPlants; TraesCS5B02G546700.1; TraesCS5B02G546700.1; TraesCS5B02G546700.
DR Gramene; TraesCAD_scaffold_043068_01G000100.1; TraesCAD_scaffold_043068_01G000100.1; TraesCAD_scaffold_043068_01G000100.
DR Gramene; TraesCLE_scaffold_023184_01G000200.1; TraesCLE_scaffold_023184_01G000200.1; TraesCLE_scaffold_023184_01G000200.
DR Gramene; TraesCS5B02G546700.1; TraesCS5B02G546700.1; TraesCS5B02G546700.
DR Gramene; TraesCS5B03G1320000.1; TraesCS5B03G1320000.1.CDS; TraesCS5B03G1320000.
DR Gramene; TraesRN5B0101290500.1; TraesRN5B0101290500.1; TraesRN5B0101290500.
DR Gramene; TraesROB_scaffold_090070_01G000200.1; TraesROB_scaffold_090070_01G000200.1; TraesROB_scaffold_090070_01G000200.
DR Gramene; TraesWEE_scaffold_025120_01G000100.1; TraesWEE_scaffold_025120_01G000100.1; TraesWEE_scaffold_025120_01G000100.
DR OMA; PDICRDS; -.
DR Proteomes; UP000019116; Chromosome 5B.
DR Proteomes; UP000815260; Chromosome 5B.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF851; 3-BETA HYDROXYSTEROID DEHYDROGENASE_ISOMERASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 10..151
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 226 AA; 24968 MW; 393D25097DEAF41B CRC64;
MSSGTGKAEL LDPAVNRTLN VLRSCKKASI KRVIVTSSMA AVAYNGKPRT PDVVVDETWF
SSPEVCEKNK QWYVLSKTLA EEAAWKYAND NGLEIITINP TMVIGPLLQP TLNTIAEAIL
KFINGSSSTY ANFCFGWINV KDVALAHILA YEVPSANGRY CMVERVIHHS DLVKIIHEMY
PEFPVPDKCA DDAPFATIYQ VSKDKIRSLG MELTPLETSL KGLSRA
//
