ID A0A3B6LY34_WHEAT Unreviewed; 1585 AA.
AC A0A3B6LY34;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_074946 {ECO:0000313|EMBL:KAF7069293.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5B02G534000.2};
RN [1] {ECO:0000313|EMBL:KAF7069293.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7069293.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5B02G534000.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5B02G534000.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5B02G534000.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7069293.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7069293.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022224; KAF7069293.1; -; Genomic_DNA.
DR SMR; A0A3B6LY34; -.
DR STRING; 4565.A0A3B6LY34; -.
DR EnsemblPlants; TraesCS5B02G534000.2; TraesCS5B02G534000.2; TraesCS5B02G534000.
DR Gramene; TraesCS5B02G534000.2; TraesCS5B02G534000.2; TraesCS5B02G534000.
DR Gramene; TraesCS5B03G1296000.2; TraesCS5B03G1296000.2.CDS; TraesCS5B03G1296000.
DR OrthoDB; 1124059at2759; -.
DR Proteomes; UP000019116; Chromosome 5B.
DR Proteomes; UP000815260; Chromosome 5B.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 3.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR032838; Vwaint_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF102; EXPRESSED PROTEIN; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13768; VWA_3; 3.
DR Pfam; PF14624; Vwaint; 1.
DR SMART; SM00220; S_TKc; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF53300; vWA-like; 3.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 24..315
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 756..935
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 1193..1362
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 1566..1585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 657..684
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 52
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1585 AA; 177024 MW; EC7094D81758485F CRC64;
MASNDSTEPT SLTIQKIREM TDNFSEQRAL GQGAYGKVYK GVHANGEEIA VKLLYNNIQT
PNDEQFQHEF DNLMMLNHRN IVRLVGYCYE TQRQHVDFHG RIVFGETTYK ALCFEYMHNG
SLQRHLSDEF HGLDWKKRYN IIKGACEGLK YLHEGFRKPI YHLDLKPDNI LLDENMIPKL
ADFGLSKLFG EEQTRVTNSP AGTIGYLPPE YLFGHIVSKK LDVFSLGVVI TKIIAGPKGH
TRSAEMPYQE FLDQVHQNWR TRLEATCTSS RILDAYCEQV TICTEIGVSS MEVDRYKRPS
ILDIIQRLDE TEAMIEKAIS WSANSSSSMP VKSQSENNDN QVRVEAFARN KAIQLAETCD
QFPVLVRVSR RALWGRAKEM LSAGIDVVLV FNAPKQAVKE VITKFMDELG PNDRLSILFV
GQNSTQQVTE LTYMSAHGRD VANHEISKLV ALYCGTVHEG HVLQKAAEVL RQRGVEESSN
RTGCILHVWV GWTFLEMFKQ EISPEFPVHT IALGDHNRRD MNLIAEKTSG TYSSIENQNT
IAHVVTQWAA QWPDRITIQA DEGVTISSIV SGCYGNLLSS DKRSAIVALN KICAGEQKTF
VVYLTVPQGK EKLVTVGGQY QGKELVGMDV VIIRPRRKCL PDEMIIHPKV AAELLRIQLM
KARLDKHRSK MEALYGETKD LDEQSNAQED VEDMRSRYGQ SEVFQQTVEQ QHIQVQGFAR
SKAIMGSKTY TEFTVLVRVS AAPWHHAQEM PRDGVDLVAV LDVSRSMQAE MLESVKQAMM
IVIDKLGPDD RLSIVLLLQT HKRRLLELTY MSDDHGHGRD AARFKISQLK ASDGRCTSHI
ASAALQEGAQ ILKGRGTEEI SGRLGCMIFL SDGEYPEILQ MQISPEFLVH TFGLGADHNS
NVMKYIADMT SGTYSFVDQD ISNVKDALVL FITGLTSIAA TSIMISLVAN LGTSISSIES
GNYNHNVKGD KNSGTININH IYAGERKEFI INLIVGAGKK RLMTIGGQYQ GFHGSKKFLD
ETDMSVLRPW LTRSPDYMEI HPDVAAEIAR IRLRNGVSDM LEKQHLTGQG LEQLWNMIKH
SDEGRGAPEK TLSGLSMDID EMKRDVSGMP YTLSWLSCHK WQRATTKGAA KNCSAFRAIA
QHADEDTNLV KVETFTRSKA IPSEGPCNKF PVLVRAAVAP WSCAEEMRRL GIDIVAVLDV
SGRMQGEKLD RMKQAMKVVI DKLGVDDRLS IVSFGTHENC LMNLTYMSDH DRDVARLKIN
ELVAGGQNDM SAGLREGAQI LWWRGVERSS RVGCMMLLSD GKFPEILQTE LDREFPVHTL
GLGSDHNPKV MKYIAEMTSG TYSSFNQGIE FRDALALFIR GLTSITARSI KITLRTNEGV
TISSIESGGY THHVKSNNQS GTIEVDNISA GEQKAFIVYL RVAEGKKDLM TIGGQYLSHN
TVRHLANTGV YALRPHLECV PGDLAIHCDV AAELVRIRLE KGISAMLEQG PSGAVLQQLW
DEIMDSDEAR ATPEEALSAL SMDVTEMKRG IEHPEEYRKS GLPYTLSWLS SHNWKRATIK
GTPCSSDAAI QTTGHDADET TTLSN
//
