ID A0A3B6MIH1_WHEAT Unreviewed; 777 AA.
AC A0A3B6MIH1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=CSC1-like protein RXW8 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_075540 {ECO:0000313|EMBL:KAF7069971.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5D02G018000.1};
RN [1] {ECO:0000313|EMBL:KAF7069971.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7069971.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5D02G018000.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5D02G018000.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5D02G018000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7069971.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7069971.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; CM022225; KAF7069971.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6MIH1; -.
DR STRING; 4565.A0A3B6MIH1; -.
DR PaxDb; 4565-Traes_5DS_92A769DA3-1; -.
DR EnsemblPlants; TraesCS5D02G018000.1; TraesCS5D02G018000.1; TraesCS5D02G018000.
DR Gramene; TraesCAD_scaffold_092997_01G000200.1; TraesCAD_scaffold_092997_01G000200.1; TraesCAD_scaffold_092997_01G000200.
DR Gramene; TraesCLE_scaffold_103728_01G000200.1; TraesCLE_scaffold_103728_01G000200.1; TraesCLE_scaffold_103728_01G000200.
DR Gramene; TraesCS5D02G018000.1; TraesCS5D02G018000.1; TraesCS5D02G018000.
DR Gramene; TraesKAR5D01G0007680.1; cds.TraesKAR5D01G0007680.1; TraesKAR5D01G0007680.
DR Gramene; TraesPAR_scaffold_094242_01G000100.1; TraesPAR_scaffold_094242_01G000100.1; TraesPAR_scaffold_094242_01G000100.
DR Gramene; TraesROB_scaffold_103007_01G000100.1; TraesROB_scaffold_103007_01G000100.1; TraesROB_scaffold_103007_01G000100.
DR Gramene; TraesWEE_scaffold_142333_01G000100.1; TraesWEE_scaffold_142333_01G000100.1; TraesWEE_scaffold_142333_01G000100.
DR OMA; DRIHKNI; -.
DR Proteomes; UP000019116; Chromosome 5D.
DR Proteomes; UP000815260; Chromosome 5D.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IBA:GO_Central.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF117; CSC1-LIKE PROTEIN RXW8; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..164
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 186..345
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 356..623
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 708..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 731..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 777 AA; 88054 MW; A1F269458C12C032 CRC64;
MKISALLTSA GINIGLCVLF LSLYSVLRKQ PANVRVYFGR RISEEHSRLR EAFILERFVP
STGWIVKALR YTEEEVLAAA GLDAVAFNRM LVFSIRIFSL AALLCVFGIL PLHYYGQNIQ
HLRIPYEDLD IFTIGNVEKR SRWLWVHCLV LYILSGVACI LLYLEFRHIA RLRLLHLKRA
TPNPGQFTVL VRGIPKTKKE SCSSAVDDFF TKYHASSYLF HQIVYKTGKV QKIMTGAKKA
CRKLKNFTDT TVDQSCKAIT YRCCLCGASS NSFQLLPTDE VVPSRGKVDL DDSSLNIDNE
ECAAAFVFFK TRYGALVASD VLQTSNPTKW VTDLAPEPND VYWSNIWLPY KQLWIRRIAT
LLGSIVFMLL FLAPVTFING LSQLDQLQKR LPFLNGILKQ PHHLVQLITG YLPSVILQIF
LYTVAPIMML FSTLEGPISH SERKRSACCK VLYFLIWNVF FVNVVSGTVL KQLDFFSSPK
DIPVQLAKVI PGQASFFITY VLTSGWASLS SELMQLFGLI YNFIRKYVLR MKEDTEFVPS
FPYHTEVPKV LLFGLLGFTC SVLAPLILPF LLVYFFLGYV VYRNQLLNVY RTRYDTGGLY
WPIIHNTVIF SLVLTQIICL GVFGLKVSPV AAGFTIPLII FTLLFNQYCR TRLLPLFSTF
PAQNLIDMDR EDELSGRMEH IHHGLHTAYC QFPESEDIQL EEIRTVGNDE DGGGCSSGGS
NGKGCSDEPS GKETLQEQQQ PRRDLSHPTL KGLPVSRLQT AVRCVTFLIR LQKRGLS
//
