ID A0A3B6MKH2_WHEAT Unreviewed; 1462 AA.
AC A0A3B6MKH2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=CFC21_075386 {ECO:0000313|EMBL:KAF7069807.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5D02G005300.1};
RN [1] {ECO:0000313|EMBL:KAF7069807.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7069807.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5D02G005300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5D02G005300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5D02G005300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7069807.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7069807.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022225; KAF7069807.1; -; Genomic_DNA.
DR SMR; A0A3B6MKH2; -.
DR STRING; 4565.A0A3B6MKH2; -.
DR EnsemblPlants; TraesCS5D02G005300.1; TraesCS5D02G005300.1; TraesCS5D02G005300.
DR Gramene; TraesCAD_scaffold_030370_01G000100.1; TraesCAD_scaffold_030370_01G000100.1; TraesCAD_scaffold_030370_01G000100.
DR Gramene; TraesCLE_scaffold_030774_01G000100.1; TraesCLE_scaffold_030774_01G000100.1; TraesCLE_scaffold_030774_01G000100.
DR Gramene; TraesCS5D02G005300.1; TraesCS5D02G005300.1; TraesCS5D02G005300.
DR Gramene; TraesCS5D03G0027200.1; TraesCS5D03G0027200.1.CDS; TraesCS5D03G0027200.
DR Gramene; TraesKAR5D01G0005420.1; cds.TraesKAR5D01G0005420.1; TraesKAR5D01G0005420.
DR Gramene; TraesKAR5D01G0005420.2; cds.TraesKAR5D01G0005420.2; TraesKAR5D01G0005420.
DR Gramene; TraesPAR_scaffold_027280_01G000100.1; TraesPAR_scaffold_027280_01G000100.1; TraesPAR_scaffold_027280_01G000100.
DR Gramene; TraesROB_scaffold_048476_01G000100.1; TraesROB_scaffold_048476_01G000100.1; TraesROB_scaffold_048476_01G000100.
DR Gramene; TraesWEE_scaffold_063132_01G000100.1; TraesWEE_scaffold_063132_01G000100.1; TraesWEE_scaffold_063132_01G000100.
DR OrthoDB; 340610at2759; -.
DR Proteomes; UP000019116; Chromosome 5D.
DR Proteomes; UP000815260; Chromosome 5D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45707; C2 CALCIUM/LIPID-BINDING PLANT PHOSPHORIBOSYLTRANSFERASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR45707:SF83; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 38..314
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 316..336
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 66
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1462 AA; 164497 MW; BAAAD70890E45075 CRC64;
MDRQAIASKS ELEHILLDEG AEPKALPLSL LEHITSSFSA DKEIGDGGFA RVYKGVLDNG
TVAVKKLFGT VDLDEKKFSE EVRCLMKAKH KNIVRFLGYC SDTQGEMVDC EGKLVLADVR
KRLLCFEYLP KGSLDKQITD ASCGLEWSKR YQIISGICDG LYYLHQNHIV HLDLKPANIL
LHDNMMPKIA DFGLSRCFDE KQSQTITSNM LGTIGYLAPE FYARRQITFK LDIYSLGMVI
IEILTGEKGY ANIDNVLERW RSRLDKSQED KQLVQVRVCT EIAIECTDFN PAKRPDAHHI
IDRLGATRNA DEFATETEAN SSSSVPKLAA VSPGPTICPE NAMDNELKKS TEELFSMTDQ
IQCFSSMPDD SSNVQLDTGI RETTSDVEEA LIIGRTEEKQ KIVATLSESI TPEVTILPIY
GFGGIGKTTL AQLVFNDSQF AGYSRVWVYV SQNFDLNKIG NSIISQLSEE SHVTEKQMIH
NHLRKLLAGK KILIVLDDVW EKNPDTLKSL KAMLRLGADS MVKIIVTTRD EAIAREICHT
VEPYKLETLT DKFCWKILKQ KTAFKNRVDK KQLKHIGREI ATKCGGVALA AQSLGYTLNG
KTSDEWESVR DNYIWTVPTP EDPSSKNHEV QASLLLSYHH MPECLKMCFS YCAIFPKGHN
IVKCDLIHQW IALGFIEPST IFDTMQLGEK YVTQLLGMSF LQYSKTPSSD GRRDKGVTLF
TLHDLVHDLA AAMLADKVNK KGNAVESSCH YALVTDCSKP LQLSTSSPEN TYFKKTFYPF
QKRSSTEKIK ALFFLNCGKI ELRGGAFSPA KCLLVLDLSE CFIRKLPSSI GQLKQLRYLH
APRIQDQENP NCISELSQLS YLNLGDSHCI SALPESIGDM KGLMHLDLSG CVGISDLPKS
FAKLKQLVYL DLSYCKMSIS EALGGFTKLQ HLNLSDKFTM HTKHIIGHPE VIGNLIKLRY
LNLSWCMDVV APDQINSLVC CISTLSNLEH LDLSCNTGIC SIPESIGNLR KLHTLDLSGC
YNLKKLPDSM VNMVSLKDLF VEEELTLDEP LLPRLNCASL PHFVVHASSD KCCSNIILLQ
PTNPDKLTID ALENVKSAEE AHSIKLIEKQ KMKRLTFQWT VAAGRFVDDE EVLEKLVPPS
SVQKLSITGY NSLSLPDWFV GIRQYLPNLC VIKLRNFPKC KNLPPLGQLP NLQELCLRGM
PCLEEWNMAY TSGEKFANEL MFPKLQRLDI RKCAKLRIKL CLCRAMILFI VDCDNVLSSW
GEILSHNSAS SSSPITNLNV SDSKLFHHLP APHSLAIRFR NDLTTLPENR QQFSSLQSLS
LRLGRSNEAE LPRWLFELTS LQELEISHPK LEKLNEDTRQ LTGLQSLSLS HCESMASLPE
WLGELTSLKR FQIKYCKGIR SLPDSIRKLT NLEYLAIDGC STLRKWCESQ ENKMKLAHIR
WKHLVLDNAH EEHIPEYGTA GL
//
