ID A0A3B6MNW7_WHEAT Unreviewed; 398 AA.
AC A0A3B6MNW7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Acetyl-CoA C-acetyltransferase {ECO:0008006|Google:ProtNLM};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5D02G173800.1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS5D02G173800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5D02G173800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5D02G173800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
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DR AlphaFoldDB; A0A3B6MNW7; -.
DR SMR; A0A3B6MNW7; -.
DR STRING; 4565.A0A3B6MNW7; -.
DR PaxDb; 4565-Traes_5DL_FCF08AEA6-1; -.
DR EnsemblPlants; TraesCS5D02G173800.1; TraesCS5D02G173800.1; TraesCS5D02G173800.
DR Gramene; TraesCAD_scaffold_022476_01G000300.1; TraesCAD_scaffold_022476_01G000300.1; TraesCAD_scaffold_022476_01G000300.
DR Gramene; TraesCLE_scaffold_027587_01G000100.1; TraesCLE_scaffold_027587_01G000100.1; TraesCLE_scaffold_027587_01G000100.
DR Gramene; TraesCS5D02G173800.1; TraesCS5D02G173800.1; TraesCS5D02G173800.
DR Gramene; TraesCS5D03G0421800.1; TraesCS5D03G0421800.1.CDS; TraesCS5D03G0421800.
DR Gramene; TraesKAR5D01G0197340.1; cds.TraesKAR5D01G0197340.1; TraesKAR5D01G0197340.
DR Gramene; TraesPAR_scaffold_043481_01G000100.1; TraesPAR_scaffold_043481_01G000100.1; TraesPAR_scaffold_043481_01G000100.
DR Gramene; TraesRN5D0100441700.1; TraesRN5D0100441700.1; TraesRN5D0100441700.
DR Gramene; TraesROB_scaffold_048839_01G000100.1; TraesROB_scaffold_048839_01G000100.1; TraesROB_scaffold_048839_01G000100.
DR Gramene; TraesWEE_scaffold_036203_01G000100.1; TraesWEE_scaffold_036203_01G000100.1; TraesWEE_scaffold_036203_01G000100.
DR OMA; YGPSMEA; -.
DR OrthoDB; 396938at2759; -.
DR Proteomes; UP000019116; Chromosome 5D.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IBA:GO_Central.
DR GO; GO:0006635; P:fatty acid beta-oxidation; IBA:GO_Central.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919:SF162; ACETYL-COA ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|RuleBase:RU003557}.
FT DOMAIN 8..266
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 276..396
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 92
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 354
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 384
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 398 AA; 40876 MW; 8F9D555A8738E055 CRC64;
MSSDARDVCV VGVARTPMGS FLGGLSSLPA TKLGSIAIEA ALRRANVDPS LVQEVFFGNV
LSANLGQAPA RQAALGAGIP NTVVCTTVNK VCASGMKATM FAAQSIQLGI NDIVVAGGME
SMSNAPKYIA EARKGSRFGH DSLVDGMLKD GLWDVYGDYA MGVCAELCAD NHALTREDQD
AYAIQSNERG IAARDSGAFA WEIVPIEVPV GRGKPAVLVD KDESLDKFDA AKLKKLRPAF
KDNAGTVTAG NASSISDGAA ALVLVSGKKA QELGLHVLAR IKGFADAAQA PELFTTTPAL
AIPKALTNAG LESSRVDFYE INEAFSAVAL ANQKLLGIPS EKINVHGGAV SLGHPLGCSG
ARILVTLLGV LREKSGKIGV AGVCNGGGGA SALVMELA
//
