ID   A0A3B6MQV4_WHEAT        Unreviewed;       907 AA.
AC   A0A3B6MQV4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=AAA+ ATPase domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5D02G189800.2};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCS5D02G189800.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCS5D02G189800.2};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCS5D02G189800.2}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   AlphaFoldDB; A0A3B6MQV4; -.
DR   EnsemblPlants; TraesCS5D02G189800.2; TraesCS5D02G189800.2; TraesCS5D02G189800.
DR   Gramene; TraesCS5D02G189800.2; TraesCS5D02G189800.2; TraesCS5D02G189800.
DR   Gramene; TraesCS5D03G0451300.3; TraesCS5D03G0451300.3.CDS; TraesCS5D03G0451300.
DR   Proteomes; UP000019116; Chromosome 5D.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0050832; P:defense response to fungus; IEA:InterPro.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039203; RGA2/3-like.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   PANTHER; PTHR36766:SF55; NB-ARC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR36766; PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8; 1.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT   DOMAIN          12..96
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          176..395
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   907 AA;  101546 MW;  26C9AFF25BA45273 CRC64;
     MVGTEMLAAA AVSQVARKIG EIIGAAQGEV TLCCSFSDDL ESIKDTLVYL EDLLKNAERN
     SFGSERANLR HWLAQIKSLA FDIEDMVDDY YSSKEQFEGS SSYAQKGSLF CSLSNPVISK
     VSMVHKMKSK RELLQTRQHL PNQYHFISHI NSVVDFDEKQ TTSYRNSDIT LFGRDRDLEN
     LMNMIMQKSV GEISIISIVG PMGLGKTSLA QLVFNDARTK AFSFRIWVHV SMGNVSLEKI
     GRDIVSQTTE RIEGNMQLQS IKNAVRTILN KYSCLIVLDS LWGKDEEVNE LKQMLLTGIQ
     TESKIVVTTH SYKVAELVST VPPYKLSALS EDDCLNIFSQ RAMAGRGDPL FREYGEEIVR
     RCGGTPLVAN FLGSVVNAQR QRREIWKAAK DKEMWKIEED YPEDKISPLF PSFKIIYYNM
     PHELRLCFVY CSIFPKGSVI DKKKLIQQWI ALDMIESRHG TLPHDVTAEK YIDELKAIYF
     LQVIERHQLK QLRYLDASTL SITTLPPQFS SFNKLQALDL SETELMELPS FLSNLKGLNY
     LNLQGCQKLQ ELKSLDLLHD LHYLNLSCCP EVRSFPESIE NLTKLRFLNL SWCSKLPTLP
     NRLLQSFASL CSLVDLNLSG FEFQMLPEFF GNICSLQYLN LSECSKLEEL PQSFGQLAYL
     KALNLSSCPD LKILGSFECL TSLQFLNLSN CTSLEYLPLC LKKLQNLDVS GCQDGIVQSC
     SSSSGSSPTH QFSEQAEQVR LSIVTSEIIP EAPVIGDLKG KKKLASASGL DVVPEVVTKP
     NETGDTPLIP GRPFSLSSSH SSSFASSSRA PLAYVSSSDV SKNNNLVPNG EITGTQFNEK
     CQEPQDLIKD VLITEENICS LDTPVHVHEL ATVEGDDDGH VIKYNGVYQH SVLCDRPNQG
     VVVQQSN
//