ID A0A3B6MR45_WHEAT Unreviewed; 414 AA.
AC A0A3B6MR45;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN ORFNames=CFC21_077093 {ECO:0000313|EMBL:KAF7071859.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5D02G164400.1};
RN [1] {ECO:0000313|EMBL:KAF7071859.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7071859.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5D02G164400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5D02G164400.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS5D02G164400.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7071859.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7071859.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR EMBL; CM022225; KAF7071859.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6MR45; -.
DR SMR; A0A3B6MR45; -.
DR STRING; 4565.A0A3B6MR45; -.
DR EnsemblPlants; TraesCS5D02G164400.1; TraesCS5D02G164400.1; TraesCS5D02G164400.
DR Gramene; TraesCLE_scaffold_044366_01G000300.1; TraesCLE_scaffold_044366_01G000300.1; TraesCLE_scaffold_044366_01G000300.
DR Gramene; TraesCS5D02G164400.1; TraesCS5D02G164400.1; TraesCS5D02G164400.
DR Gramene; TraesKAR5D01G0185260.1; cds.TraesKAR5D01G0185260.1; TraesKAR5D01G0185260.
DR Gramene; TraesROB_scaffold_082011_01G000300.1; TraesROB_scaffold_082011_01G000300.1; TraesROB_scaffold_082011_01G000300.
DR Gramene; TraesWEE_scaffold_100490_01G000300.1; TraesWEE_scaffold_100490_01G000300.1; TraesWEE_scaffold_100490_01G000300.
DR OMA; FANNWEV; -.
DR OrthoDB; 1214460at2759; -.
DR Proteomes; UP000019116; Chromosome 5D.
DR Proteomes; UP000815260; Chromosome 5D.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005:SF100; LIPASE-RELATED; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid degradation {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid metabolism {ECO:0000256|PIRNR:PIRNR000862};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..414
FT /note="Lipase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039993301"
FT DOMAIN 54..108
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT ACT_SITE 183
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 352
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 381
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ SEQUENCE 414 AA; 45579 MW; 6EDB4F1E3DDCE496 CRC64;
MAVPGGGAAA ALALTLLLLL RSCVSGATHA SSALRHAVPR GDAGGGLCGQ LLLPLGYPCT
EHTVETDDGF LLSLQHIPHG KNGVPDNTGP PVFLQHGLFQ GGDTWFINSA EQSLGYILAD
NGFDVWIGNV RGTRWSKGHS TFTVHDKLFW DWSWQELAEY DLLAMLSYVY TVRQSKILYV
GHSQGTIMGL AAFTLPEITK MISAAALLCP ISYLDHVSAS FVLRAVGMHL DQMLLTMGFH
QLNFRSDMGV QIVDSICDDG HVDCNDLLSS ITGENCCFNG SRIDHYLEYE PHPSSTKNLH
HLFQMIRKGT FARYDYGLWG NLRRYGKLSP PPFDLSSIPE SLPMWMGYGG LDALADVTDV
ARTVKELRST PELLYISGYG HIDFVMSVKA KDDVYVDLMQ FLRLRANGSL HSSY
//
