ID A0A3B6MRS4_WHEAT Unreviewed; 562 AA.
AC A0A3B6MRS4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS5D02G207500.1.cds1};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS5D02G207500.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS5D02G207500.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS5D02G207500.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR AlphaFoldDB; A0A3B6MRS4; -.
DR SMR; A0A3B6MRS4; -.
DR STRING; 4565.A0A3B6MRS4; -.
DR EnsemblPlants; TraesCS5D02G207500.1; TraesCS5D02G207500.1.cds1; TraesCS5D02G207500.
DR Gramene; TraesCLE_scaffold_104190_01G000300.1; TraesCLE_scaffold_104190_01G000300.1; TraesCLE_scaffold_104190_01G000300.
DR Gramene; TraesCS5D02G207500.1; TraesCS5D02G207500.1.cds1; TraesCS5D02G207500.
DR Gramene; TraesCS5D03G0487900.1; TraesCS5D03G0487900.1.CDS1; TraesCS5D03G0487900.
DR OMA; HGSMRFR; -.
DR OrthoDB; 469241at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000019116; Chromosome 5D.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315:SF79; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 3.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 2.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 55..126
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 300..339
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 343..387
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 562 AA; 58673 MW; 92AA0EA2F4ACBE37 CRC64;
MGAARPRRWR FPFQRSAPSS PSSKSLPPAP YSPARSAAAA YPEPERRWAQ QEEEAAPPEF
VCPLSGALMA DPAILPSGQT YERACLQACA ELSFLPPGAG SGSDAMIPNS ALKAAIGSWC
ARSGRASPRP PSKEAVREAV LRAMPPAAAA AAEAKSVRTR RAAMASSSNS SYSSPASAAS
TSTYTSSSEI TPPEEDAAAK PVKEAAKEVE LPVDPLEDEV VATVMDADED GEVAAALAVL
RDATRESAER RLALCTPRLL AALRRVLLIP RHASARIDAT AALVNLSLEP ANKVRIVRAG
AVPALVEVLR SGGSAPEARE HAAGALFGLA LNEENRAAIG VLGAVPPLLD LLTSPAHHPR
ARRDAGMAIY HLSLAAVNQS KVARFPGASK ALLSVASSAA EPTPIRRLAL MVICNVGACS
EGRASLMDAG AVAAVSGILL CPHDDSTRVT LAELEEWCVA AIYALSRGSL RFRGLARAAG
ADRALRRVAE EGTPGGVRRE MARKTLRAMR GDLDEEADLT SSSLECGDGE DCGGSIVSDG
LMSFRRRQRE VGASSCGNTA EF
//
