ID A0A3B6NIT7_WHEAT Unreviewed; 460 AA.
AC A0A3B6NIT7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_081421 {ECO:0000313|EMBL:KAF7076818.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6A02G009500.1};
RN [1] {ECO:0000313|EMBL:KAF7076818.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7076818.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS6A02G009500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS6A02G009500.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS6A02G009500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7076818.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7076818.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022226; KAF7076818.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6NIT7; -.
DR SMR; A0A3B6NIT7; -.
DR STRING; 4565.A0A3B6NIT7; -.
DR EnsemblPlants; TraesCS6A02G009500.1; TraesCS6A02G009500.1; TraesCS6A02G009500.
DR Gramene; TraesCS6A02G009500.1; TraesCS6A02G009500.1; TraesCS6A02G009500.
DR Gramene; TraesCS6A03G0019000.1; TraesCS6A03G0019000.1.CDS; TraesCS6A03G0019000.
DR OMA; CYSIQEH; -.
DR Proteomes; UP000019116; Chromosome 6A.
DR Proteomes; UP000815260; Chromosome 6A.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1181; OS08G0235651 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 1..90
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 164..403
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT COILED 19..46
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 107..134
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 460 AA; 51847 MW; 880726560C9AAB50 CRC64;
MSSLLPKLGE LLVEEYKLKK SVKKGIEELK AELESMQAAL IKVSSVPLDQ LDPQVKIWAN
EVRELSYAIE DSLDSFVTRV EGNEPTKPKI KHLLKKARNE FSKFKARHEI ANDIKDIQSQ
VRKIKERRDS YKIDDVDANP AATTVDPRLP ALYKKLSDLV GIDKPINELI KILSEGVPMP
DKNPKIVSIV GFGGLGKTTL AKALYDKLST KYQRVTTYQC HGFVPVGQNP KAKKVLLDIV
CELDKELYKA ATTMDERQLI NELQTFLAGK RYFIVIDDIW DTQIWETIKC AFMDSHPESR
LIITTRIVDV ATKAGGIYHM QPLSDDYSKI LFYTRTSGSE GPAEVTTKIL KKCGGVPLAI
TTIASLLVGK HTEDWSKVYD AIGFGHADNG DVHNTRKILS FSYYDLSSNL KTCLLYLSVF
PEDYLINKIS LIWRWVAEGF IPYGEGMNHL NLERSISTSL
//
