ID A0A3B6NRC8_WHEAT Unreviewed; 387 AA.
AC A0A3B6NRC8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=Fatty acid desaturase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_084213 {ECO:0000313|EMBL:KAF7080075.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6A02G280700.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF7080075.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7080075.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS6A02G280700.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS6A02G280700.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS6A02G280700.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7080075.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7080075.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC {ECO:0000256|ARBA:ARBA00009295}.
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DR EMBL; CM022226; KAF7080075.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6NRC8; -.
DR STRING; 4565.A0A3B6NRC8; -.
DR EnsemblPlants; TraesCS6A02G280700.1; TraesCS6A02G280700.1.cds1; TraesCS6A02G280700.
DR Gramene; TraesCAD_scaffold_006080_01G000200.1; TraesCAD_scaffold_006080_01G000200.1; TraesCAD_scaffold_006080_01G000200.
DR Gramene; TraesCLE_scaffold_010192_01G000100.1; TraesCLE_scaffold_010192_01G000100.1; TraesCLE_scaffold_010192_01G000100.
DR Gramene; TraesCS6A02G280700.1; TraesCS6A02G280700.1.cds1; TraesCS6A02G280700.
DR Gramene; TraesCS6A03G0747100.1; TraesCS6A03G0747100.1.CDS1; TraesCS6A03G0747100.
DR Gramene; TraesKAR6A01G0311730.1; cds.TraesKAR6A01G0311730.1; TraesKAR6A01G0311730.
DR Gramene; TraesPAR_scaffold_004394_01G000100.1; TraesPAR_scaffold_004394_01G000100.1; TraesPAR_scaffold_004394_01G000100.
DR Gramene; TraesRN6A0100726600.1; TraesRN6A0100726600.1; TraesRN6A0100726600.
DR Gramene; TraesROB_scaffold_055271_01G000100.1; TraesROB_scaffold_055271_01G000100.1; TraesROB_scaffold_055271_01G000100.
DR Gramene; TraesWEE_scaffold_057114_01G000100.1; TraesWEE_scaffold_057114_01G000100.1; TraesWEE_scaffold_057114_01G000100.
DR OMA; DTVFVPW; -.
DR Proteomes; UP000019116; Chromosome 6A.
DR Proteomes; UP000815260; Chromosome 6A.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd03507; Delta12-FADS-like; 1.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR021863; FAS_N.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR32100:SF48; -; 1.
DR PANTHER; PTHR32100; OMEGA-6 FATTY ACID DESATURASE, CHLOROPLASTIC; 1.
DR Pfam; PF11960; DUF3474; 1.
DR Pfam; PF00487; FA_desaturase; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..72
FT /note="Fatty acid desaturase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11960"
FT DOMAIN 91..352
FT /note="Fatty acid desaturase"
FT /evidence="ECO:0000259|Pfam:PF00487"
SQ SEQUENCE 387 AA; 44825 MW; 6E29B1DFB6DD63E5 CRC64;
MGAGGRMTEK EREKQELLGR TGVGAAFQRS PTDKPPFTLG QIKMAIPPHC FQRSLVKSSS
YLVHDLVIVA ALLYAALVWI PALPSMLQLG AWPLYWVAQG CVMFGVWVIA HECGHHAFSD
YPLLDDIVGL VLHSWLLVPY FSRKHSHRRH HSNTGSLERD EVFVPRPKEA LPWYTPYIHD
NPVVRVVLIM VQLTLGWYMY LSLNTWGRPY PRFACHFDPY SPIYNDRERP QIFISDVGVL
AVSFAMLDFV STFGFWWMMR VYGAPLMIVN AWLVLVTYLH HTHPALPHYD STEWDWLRGA
LATMDRDYGI LNRVFHNITD THILHHLFSN IPHYHAMEAT KAIKPILGEY YQIDRTPLAK
ATWREAKECL YIVREDSKGI FWYSNKF
//
