ID A0A3B6PLI2_WHEAT Unreviewed; 389 AA.
AC A0A3B6PLI2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Chalcone synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_087741 {ECO:0000313|EMBL:KAF7084046.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6B02G185200.2};
RN [1] {ECO:0000313|EMBL:KAF7084046.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7084046.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS6B02G185200.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS6B02G185200.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS6B02G185200.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7084046.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7084046.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; CM022227; KAF7084046.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6PLI2; -.
DR SMR; A0A3B6PLI2; -.
DR STRING; 4565.A0A3B6PLI2; -.
DR PaxDb; 4565-Traes_6BS_91A668B50-2; -.
DR EnsemblPlants; TraesCS6B02G185200.2; TraesCS6B02G185200.2; TraesCS6B02G185200.
DR Gramene; TraesCS6B02G185200.2; TraesCS6B02G185200.2; TraesCS6B02G185200.
DR Gramene; TraesCS6B03G0471600.2; TraesCS6B03G0471600.2.CDS; TraesCS6B03G0471600.
DR Gramene; TraesRN6B0100459900.2; TraesRN6B0100459900.2; TraesRN6B0100459900.
DR OrthoDB; 5817at2759; -.
DR Proteomes; UP000019116; Chromosome 6B.
DR Proteomes; UP000815260; Chromosome 6B.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IBA:GO_Central.
DR GO; GO:0009813; P:flavonoid biosynthetic process; IEA:UniProt.
DR GO; GO:0030639; P:polyketide biosynthetic process; IBA:GO_Central.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF111; OS04G0103900 PROTEIN; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 8..221
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 230..382
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 157
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 389 AA; 42769 MW; 10B7EC3A95C24E01 CRC64;
MGFCVSGTRA TIMGIGTAVP TNVLQQSSFS DYYFETTNSN HMVDLKAKFA NICEKTMIEK
RHLYMSDEFI RSSPSITAYN SPSLNLRQGL ADAAIPQLGA EAARHAIADW GRQASNITHL
VFCTTVSGCM PGADFELIKL LDLPLSTRRF MLYQAGCHGA GISMRLAKDL AENNHGSRVL
VVCSEVITMA FRGPSKSHMG NLVGQAIFDD AAGAIIIGAE PTGNERPLFE MVSASQDIIP
GTEEMVVSKL YEDGIVYTLH RDVALHISRN IEGRVKKALE RASLLTKDWN EELFWVVHPG
GREILDKVES SLVLRKEKMD VSRKVMAQHG NTLSSCVIVV MDEMRKRSRK RGLPTAGEGL
EWGLLFSFGP GLTVETILLR ALHNQEPNA
//
