ID   A0A3B6PPB3_WHEAT        Unreviewed;       873 AA.
AC   A0A3B6PPB3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=MIF4G domain-containing protein {ECO:0000259|SMART:SM00543};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6B02G259600.3};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCS6B02G259600.3}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCS6B02G259600.3};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCS6B02G259600.3}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
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DR   AlphaFoldDB; A0A3B6PPB3; -.
DR   EnsemblPlants; TraesCS6B02G259600.3; TraesCS6B02G259600.3; TraesCS6B02G259600.
DR   Gramene; TraesCS6B02G259600.3; TraesCS6B02G259600.3; TraesCS6B02G259600.
DR   Gramene; TraesCS6B03G0763000.3; TraesCS6B03G0763000.3.CDS; TraesCS6B03G0763000.
DR   Proteomes; UP000019116; Chromosome 6B.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 3.
DR   SMART; SM00543; MIF4G; 3.
DR   SUPFAM; SSF48371; ARM repeat; 3.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT   DOMAIN          65..287
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          473..661
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          676..872
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          322..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          387..463
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        9..27
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        329..346
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        387..407
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        422..463
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   873 AA;  100051 MW;  8A3B7AA2943A756C CRC64;
     MESSQTENLT DTKQDDDARQ SKQEDEEARI EEYKKLMDQK IALRRNNQNP ERPDANYLRT
     LDSSIKRNTT VIKKLKTIND EQKDGLMDEL KSVNLSKFVS EAVSYICEAK LRSADIQAAV
     QVCSLLHQRY KDFSPCLIQG LLKVFLPGKS GDDLDTDKNS RAMKKRSTLK LLIELYFVGI
     VEDASIFVNI IKDLTSLEHL KDREATQTNL SLLSSFVRQG RLFIGLRSHG HESYDEFFKD
     LNVTADQKKF FKKALNSYYD AVSELLQSEN ASLRLMEAEN AKVLSAKGEL SDENTASYEK
     LRKSFDQLLR GVSSLAEAID LQPPVMPDDG NTTRVTTGTD VTPSSGKEPS VLEPIWDDDD
     TKTFYESLPD LRAFVPAVLL GEAEQKLNEQ HAKGREQSSE SNAEQETEVH DNAQTSSATE
     DQLEGKADDV AKDSEEKEKD KGKEAEKSKE KDLDRKTEKD KEKVRALDGG SLDNLLQRLP
     GCVSRDLIDQ LTVEFCYLNS KASRKKLVRA LFSVPRTSLE LLPYYSRMIA TLSSCMKDVP
     TMLLPMLEEE FNFLINKKDQ INIETKIKNI RFIGELCKFK IAPAALVFSC LKACLDDFSH
     HNIDVACNLL ETCGRFLYRS PETTIRMANM LEILMRLKNV KNLDPRHSTL VENAYYLCKP
     PERSARVSKV RPPLYQYIRK LLFSDLDKSS VEHVLRQLRK LPWVECQQYL VKCFLKVHKG
     KYSQVHLIAL LTAGLSRYHD DFAVAVVDEV LEEIRVGLEL NDYAMQQRRL AHMRFLGELY
     SYKHIDSSVV FETLYLIIMF GHGTYEQDVL DPPEDCFRIR LIITLLQTCG HYFTRGSSKR
     KLDKFLLHFQ RYIIMKGPLP LDIEFDIQEI VNW
//