ID A0A3B6PSK3_WHEAT Unreviewed; 285 AA.
AC A0A3B6PSK3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Bidirectional sugar transporter SWEET {ECO:0000256|RuleBase:RU910715};
GN ORFNames=CFC21_090093 {ECO:0000313|EMBL:KAF7086834.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6B02G421700.1};
RN [1] {ECO:0000313|EMBL:KAF7086834.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7086834.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS6B02G421700.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS6B02G421700.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS6B02G421700.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7086834.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7086834.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mediates both low-affinity uptake and efflux of sugar across
CC the membrane. {ECO:0000256|RuleBase:RU910715}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU910715}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU910715}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SWEET sugar transporter family.
CC {ECO:0000256|ARBA:ARBA00007809, ECO:0000256|RuleBase:RU910715}.
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DR EMBL; CM022227; KAF7086834.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6PSK3; -.
DR EnsemblPlants; TraesCS6B02G421700.1; TraesCS6B02G421700.1; TraesCS6B02G421700.
DR Gramene; TraesCS6B02G421700.1; TraesCS6B02G421700.1; TraesCS6B02G421700.
DR Gramene; TraesCS6B03G1183600.1; TraesCS6B03G1183600.1.CDS; TraesCS6B03G1183600.
DR OMA; EHKGDID; -.
DR OrthoDB; 73377at2759; -.
DR Proteomes; UP000019116; Chromosome 6B.
DR Proteomes; UP000815260; Chromosome 6B.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051119; F:sugar transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008643; P:carbohydrate transport; IBA:GO_Central.
DR Gene3D; 1.20.1280.290; -; 2.
DR InterPro; IPR047664; SWEET.
DR InterPro; IPR004316; SWEET_rpt.
DR PANTHER; PTHR10791:SF22; BIDIRECTIONAL SUGAR TRANSPORTER SWEET12; 1.
DR PANTHER; PTHR10791; RAG1-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF03083; MtN3_slv; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910715};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU910715};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU910715};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU910715}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 48..66
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 72..94
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 106..126
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 132..153
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 165..187
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
FT TRANSMEM 193..214
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910715"
SQ SEQUENCE 285 AA; 31178 MW; F0137B216490E63A CRC64;
MGGLSMEHPW AFAFGLLGNV ISFSSLLAPI PTFYRIFKSK STEGFQSVPY VVALFSAMLW
IFYALVKTGE GLLISINAAG CVIETVYIVM YLVYAPRKAK IFTAKIVVLL NIAGFGLIFL
LTLFAFHGET RVVSLGWICV GFSVCVFVAP LSIIGRVIKT KSVEYMPFSL SLTLTLSAVD
WFLYGLLIKD KYVALPNILG FTFGMIQMVV YMFYMNATPV VSDLKEGKEG LKMPAEEQVV
VINVGMIEKS SGAVVRPVTE MVKAVPAAPG QQVMALDSAR FVDVV
//
