ID A0A3B6PT42_WHEAT Unreviewed; 786 AA.
AC A0A3B6PT42;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Subtilisin-like protease {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_089546 {ECO:0000313|EMBL:KAF7086232.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6B02G368500.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF7086232.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7086232.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS6B02G368500.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS6B02G368500.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS6B02G368500.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7086232.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7086232.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CM022227; KAF7086232.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6PT42; -.
DR SMR; A0A3B6PT42; -.
DR EnsemblPlants; TraesCS6B02G368500.1; TraesCS6B02G368500.1.cds1; TraesCS6B02G368500.
DR Gramene; TraesCS6B02G368500.1; TraesCS6B02G368500.1.cds1; TraesCS6B02G368500.
DR Gramene; TraesCS6B03G1042200.1; TraesCS6B03G1042200.1.CDS1; TraesCS6B03G1042200.
DR Gramene; TraesKAR6B01G0417890.1; cds.TraesKAR6B01G0417890.1; TraesKAR6B01G0417890.
DR Gramene; TraesWEE_scaffold_031751_01G000300.1; TraesWEE_scaffold_031751_01G000300.1; TraesWEE_scaffold_031751_01G000300.
DR OMA; YSDMTAV; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000019116; Chromosome 6B.
DR Proteomes; UP000815260; Chromosome 6B.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF721; SUBTILISIN-LIKE PROTEASE; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..786
FT /note="Subtilisin-like protease"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040072199"
FT DOMAIN 42..125
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 149..598
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 392..475
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 675..776
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT REGION 218..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..241
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 157
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 233
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 561
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 786 AA; 81511 MW; 7D3FD1719DE56110 CRC64;
MELSLTPLAA LCVLLAFAVV AAPVAATEVE VEIRTAEVQS SYIVHVAAGH APRLPRRGLL
TTRAYGSFLR DQFPVELSSP APRVLYSYSH AATGFAARLT GRQAARLASS GSVLAVVPDV
MQELHTTLTP SFLGLSPSSR LLPASNGASD VVIGVLDTGV YPEGRASFAA DASLPPLPPG
KFRGGCVSGP SFNGSALCNN KLVGAKFFHK GQKAARGSAF GEDSESPLDT NGHGTHTSST
AGGSAVADAA FYDYARGKAV GMAPGARIAV YKVCWKGCAS SDILAAFDEA IADGVDVISL
SLGSNGKAPD FYSDMTAVGA FHAVSKGIVV SASAGNSGPK ESTAVNVAPW FLTVGASTLN
RQFPADVVLG NGETYTGTSL YAGEPLGATK IPLVHAGEVG SKICEAGKLN ATMVAGKIVF
CDPGVYARAA KEQAVKLAGG AGAIFGSPEA YGEQAMTSAY VHPATAVTFA AAEKIKKYIS
AQTSPTATIV FRGTVVGPTP PSPRMASFSS RGPNTRAAEI FKPDVTAPGV DILAAWTGAN
SPSELASDTR RVKYNIISGT SMSCPHVSGI AALLRQARPE WSPAMIKSAL MTTAYNIDSA
GGVIGDMSTG KASTPFARGA GHVDPNRAVD PGLVYDAGTE DYITFLCALG YTDKQIAVFG
SSTNCSTRAG SSVGDHNYPA FSVVFTANKL AVVRQRRVVR NVGGDARATY RAKVTAPDGV
LVTVSPRTLR FTATQKTQEY VITFAQRIFR SVKGNHTFGS IEWSDRKHTV TSPIAITWPA
SKVADM
//
