ID A0A3B6QBZ4_WHEAT Unreviewed; 768 AA.
AC A0A3B6QBZ4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_091894 {ECO:0000313|EMBL:KAF7088825.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6D02G117500.1};
RN [1] {ECO:0000313|EMBL:KAF7088825.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7088825.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS6D02G117500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS6D02G117500.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS6D02G117500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7088825.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7088825.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022228; KAF7088825.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6QBZ4; -.
DR STRING; 4565.A0A3B6QBZ4; -.
DR EnsemblPlants; TraesCS6D02G117500.1; TraesCS6D02G117500.1; TraesCS6D02G117500.
DR Gramene; TraesCS6D02G117500.1; TraesCS6D02G117500.1; TraesCS6D02G117500.
DR Gramene; TraesCS6D03G0257200.1; TraesCS6D03G0257200.1.CDS; TraesCS6D03G0257200.
DR OMA; AKGCTHG; -.
DR Proteomes; UP000019116; Chromosome 6D.
DR Proteomes; UP000815260; Chromosome 6D.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF988; OS06G0707733 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 87..146
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 270..487
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 768 AA; 87682 MW; 0AA460474994967E CRC64;
MRWVLQLVEA GAEGWYSILS DSVQPHLSGI LPQDLKPQRL VLQHLNPLTS SATMATAISA
AVWALRKALA PITDDLPKDW AASDSLGPNI NALKMELLRV QGILYNAHDR EITNPALQDL
LHMLRQLADG AEDVLDELDY FRIQDKLDST YHAADKHAKG CTHGLALNAR HTARAVANKF
KFSSGGNKQT PKLKFDRVDM SKRMADIVQQ LDPICAKVKE ILDLELRNQK PAQGNNRPKT
TSAIIEPELF GRNVQKKNIV DDITHGKYYA NGLTVLQIVG PGGIGKMTFT QHVYQEVNIL
FDIMIWICVS LNFDANRLTQ KIVKKIPKVN AENENAIEGE LIEQRLKHKR FLLVLDEWKK
LLAPFRKGEA RGNMVIVTTR IPEAVTMVKT VDYSIELNRL GTEDFMHLFE ACVFGHEQPW
KDYPELLGVG KSIVGHLKGF PLAAKTVGRL LRNQLSLDNW TRVLESKEWE LQTSDYDIMP
ALKLSYDYLP FHLQQCFSYG ALFPEDYEFG GTELVQLWIG LDILDSCDER KRLEDVGLCY
LNDLVNRGFF KKNEKEDGSS CYVMHDLLHE LAVKVSSSEC LSISSSNVRY IQSPPSVRHL
SIIIGDRDVN DRMTFEDFKR DLSTLDEKLK IENLKTLMLF GEYQGCFAQT LGVLFAEAKS
LRVILLSGAS YRYVVEDVFR SLPRLIHLRY LRITPFARLN SNISRFYHLR VLDVEQYSVQ
LDFPRDMSNL TKLRHFLVRD IDLQYINSDV GKLELLQDLR SFMVKREI
//
