ID A0A3B6QIB6_WHEAT Unreviewed; 417 AA.
AC A0A3B6QIB6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Thioredoxin domain-containing protein {ECO:0000259|PROSITE:PS51352};
GN ORFNames=CFC21_092936 {ECO:0000313|EMBL:KAF7090125.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6D02G215100.1};
RN [1] {ECO:0000313|EMBL:KAF7090125.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7090125.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS6D02G215100.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS6D02G215100.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS6D02G215100.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7090125.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7090125.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein disulfide isomerase family.
CC {ECO:0000256|ARBA:ARBA00006347}.
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DR EMBL; CM022228; KAF7090125.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6QIB6; -.
DR SMR; A0A3B6QIB6; -.
DR STRING; 4565.A0A3B6QIB6; -.
DR EnsemblPlants; TraesCS6D02G215100.1; TraesCS6D02G215100.1; TraesCS6D02G215100.
DR Gramene; TraesCAD_scaffold_070776_01G000400.1; TraesCAD_scaffold_070776_01G000400.1; TraesCAD_scaffold_070776_01G000400.
DR Gramene; TraesCLE_scaffold_060147_01G000400.1; TraesCLE_scaffold_060147_01G000400.1; TraesCLE_scaffold_060147_01G000400.
DR Gramene; TraesCS6D02G215100.1; TraesCS6D02G215100.1; TraesCS6D02G215100.
DR Gramene; TraesCS6D03G0531800.1; TraesCS6D03G0531800.1.CDS; TraesCS6D03G0531800.
DR Gramene; TraesKAR6D01G0236290.1; cds.TraesKAR6D01G0236290.1; TraesKAR6D01G0236290.
DR Gramene; TraesPAR_scaffold_047199_01G000100.1; TraesPAR_scaffold_047199_01G000100.1; TraesPAR_scaffold_047199_01G000100.
DR Gramene; TraesROB_scaffold_061450_01G000100.1; TraesROB_scaffold_061450_01G000100.1; TraesROB_scaffold_061450_01G000100.
DR Gramene; TraesWEE_scaffold_076357_01G000400.1; TraesWEE_scaffold_076357_01G000400.1; TraesWEE_scaffold_076357_01G000400.
DR OMA; YGSQISR; -.
DR OrthoDB; 1053050at2759; -.
DR Proteomes; UP000019116; Chromosome 6D.
DR Proteomes; UP000815260; Chromosome 6D.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003756; F:protein disulfide isomerase activity; IBA:GO_Central.
DR GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR GO; GO:0034976; P:response to endoplasmic reticulum stress; IBA:GO_Central.
DR CDD; cd02961; PDI_a_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 2.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR017937; Thioredoxin_CS.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR18929; PROTEIN DISULFIDE ISOMERASE; 1.
DR PANTHER; PTHR18929:SF167; PROTEIN DISULFIDE ISOMERASE-LIKE 5-3; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR PRINTS; PR00421; THIOREDOXIN.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00194; THIOREDOXIN_1; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..417
FT /note="Thioredoxin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039994504"
FT TRANSMEM 379..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..147
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 417 AA; 46458 MW; C401998BE30C6AD9 CRC64;
MPPMAVDKQR LLPLFVLALV TACLVSGGEE PARFQIPRDG SVVELDEGNF EAAVAAVDFL
FVDFHAPWCG HCKRLSPQLD EAAPVLAGLS TPIVVAKVNA EKYKKLRSKY GVDGFPTLML
FDHGVPTEYT GSRKAGQLVE SLRKLVAPDV SVLKSDAAIK SFVQEAGVGF PLFIGFGVDE
SSIAEYGARY KKKAWFSTAK DFSEDLMAVY DFDKIPALVS LNPKYNEQSV FYGPFEGTFL
EDFIRQSLLP MTVPINAETV KMLKDDDRKV VLAVLQDDSD ETSMRLIKIL RSAANANHDL
VFGYVGVNQW EEFTEPFHDS KSSQLPKLVV WDKDEKYEVV EGLEKLEEGD HGSQISRFLE
AYRAGRTIKK TFGRRFPTLL GVNALYILLL LVAVLVVLMF FSGQGEEDRQ PTRAHQE
//
