ID A0A3B6QIX4_WHEAT Unreviewed; 666 AA.
AC A0A3B6QIX4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Subtilisin-like protease {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_094012 {ECO:0000313|EMBL:KAF7091431.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS6D02G318700.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF7091431.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7091431.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS6D02G318700.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS6D02G318700.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS6D02G318700.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7091431.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7091431.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CM022228; KAF7091431.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6QIX4; -.
DR SMR; A0A3B6QIX4; -.
DR EnsemblPlants; TraesCS6D02G318700.1; TraesCS6D02G318700.1.cds1; TraesCS6D02G318700.
DR Gramene; TraesCAD_scaffold_079790_01G000200.1; TraesCAD_scaffold_079790_01G000200.1; TraesCAD_scaffold_079790_01G000200.
DR Gramene; TraesCLE_scaffold_078647_01G000100.1; TraesCLE_scaffold_078647_01G000100.1; TraesCLE_scaffold_078647_01G000100.
DR Gramene; TraesCS6D02G318700.1; TraesCS6D02G318700.1.cds1; TraesCS6D02G318700.
DR Gramene; TraesCS6D03G0742500.1; TraesCS6D03G0742500.1.CDS1; TraesCS6D03G0742500.
DR Gramene; TraesRN6D0100782600.1; TraesRN6D0100782600.1; TraesRN6D0100782600.
DR Gramene; TraesROB_scaffold_054584_01G000400.1; TraesROB_scaffold_054584_01G000400.1; TraesROB_scaffold_054584_01G000400.
DR Gramene; TraesWEE_scaffold_167397_01G000100.1; TraesWEE_scaffold_167397_01G000100.1; TraesWEE_scaffold_167397_01G000100.
DR OMA; ASKFAWV; -.
DR Proteomes; UP000019116; Chromosome 6D.
DR Proteomes; UP000815260; Chromosome 6D.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF721; SUBTILISIN-LIKE PROTEASE; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 29..478
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 271..355
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 555..656
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT REGION 98..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 37
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 113
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 441
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 666 AA; 69066 MW; 7A54A4E1C8F237C6 CRC64;
MQELHTTLTP SFLGLSPSSG LLPESNGASD VVIGVLDTGV YPEGRASFSA DPSLPPLPPG
KFRGGCVSGP SFNGSALCNN KLVGAKFFHK GQKAARGSAF GEDSESPLDT NGHGTHTSST
AGGSAVADAA FYDYARGKAV GMAPGARIAV YKVCWKGCAS SDILAAFDEA IADGVDVISL
SLGSNGKAPD FYSDTTAVGA FRAVSKGIVV SASAGNSGPR ESTAVNVAPW FLTVGASTLN
RQFPADVVLG NGETFTGTSL YAGEPLSATK KPLVHAGDVG SKICEEGKLN STMVAGKIVF
CDPGVYARAA KEQAVKLAGG AGAIFGSPEA YGEQAMTSAY VHPATAVTFA AAEKIKKYIS
AQTSPTATIV FHGTVVGPTP PSPRMASFSS RGPNTRAVEI FKPDVTMPGV DILAAWTGAN
SPSELASDTR RVKYNIISGT SMSCPHVSGI AALLRQARPE WSPAMIKSAL MTTAYNMDNA
GAVIGDMSTG KASTPFARGA GHVDPNRAVD PGLVYDAGTE DYITFLCALG YTDKQIAVFS
SSTNCSTRAG SSVGDHNYPA FSVVFTTNKL AVVRQRRVVR NVGGDARATY RAKVTAPDGV
LVTVSPRTLR FTATQKTQEY VVTFAQRIFG GVKGNHTFGS IEWSDRKHTV TSPIAITWPA
SKVADM
//
