ID A0A3B6RC81_WHEAT Unreviewed; 1348 AA.
AC A0A3B6RC81;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Disease resistance N-terminal domain-containing protein {ECO:0000259|Pfam:PF18052};
GN ORFNames=CFC21_095684 {ECO:0000313|EMBL:KAF7093261.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7A02G070800.1};
RN [1] {ECO:0000313|EMBL:KAF7093261.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7093261.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7A02G070800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7A02G070800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7A02G070800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7093261.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7093261.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022229; KAF7093261.1; -; Genomic_DNA.
DR STRING; 4565.A0A3B6RC81; -.
DR PaxDb; 4565-Traes_7AS_808877026-10; -.
DR EnsemblPlants; TraesCS7A02G070800.1; TraesCS7A02G070800.1; TraesCS7A02G070800.
DR Gramene; TraesCAD_scaffold_053435_01G000100.1; TraesCAD_scaffold_053435_01G000100.1; TraesCAD_scaffold_053435_01G000100.
DR Gramene; TraesCLE_scaffold_000275_01G000700.1; TraesCLE_scaffold_000275_01G000700.1; TraesCLE_scaffold_000275_01G000700.
DR Gramene; TraesCS7A02G070800.1; TraesCS7A02G070800.1; TraesCS7A02G070800.
DR Gramene; TraesPAR_scaffold_083142_01G000100.1; TraesPAR_scaffold_083142_01G000100.1; TraesPAR_scaffold_083142_01G000100.
DR Gramene; TraesROB_scaffold_033696_01G000200.1; TraesROB_scaffold_033696_01G000200.1; TraesROB_scaffold_033696_01G000200.
DR OMA; ANITAMK; -.
DR OrthoDB; 357655at2759; -.
DR Proteomes; UP000019116; Chromosome 7A.
DR Proteomes; UP000815260; Chromosome 7A.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1062; OS11G0647000 PROTEIN; 1.
DR Pfam; PF18052; Rx_N; 1.
DR SUPFAM; SSF52058; L domain-like; 2.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 7..86
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT REGION 148..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1348 AA; 154415 MW; 876DB2C37B7D8FFC CRC64;
MAELASGAVS SLLGVIRNEA LLLGRVRHDV QFIQEEMESM QSFLAHLSKK APGGGDQDEQ
MRTWMNQVRL LAQDSNNCID MYLYRGNPEL HLARGGLRRY VFWFPWFVHK MVAQRRAAVQ
LGVLRERAHD IGERRTRYGV EVPAKEAAAA LSPTAEEQAS ASSASSDDEK EKSNDQLMLA
VATTNHSGVR GAFYQPRTPE ENTRVKLAEW IEDVAQCGTA MGEPIPSVAV VAQDKEETLA
IANEASAMWE KRCPHWRSVM VDIPAVHIQS RTLRTRDILY YILRKLQSVE PQPQQQEGQV
GEEEAEKIRF VIRLEKWKLL DEVTEQIQAM KVDNKLSEIK NTMEQMKGGQ LQINLQQMDE
DLLGLPESVK DQPLWVLLRA LWQLKHKPIE GEPTTKQDQE WKEDRFTHEY IIKRTAEKLK
GHMEEDADTK AIRLKEAHYE QILREVFPPV TTKKNPQIQE QATAVSATST IILVEDQIKE
MIRKVLQEKS VHKPGAELQE DKTMKKPGPA ELQEDKSMKK IDTTDGIQSQ HCIPNALIEE
TIAKIQEIEC TMQDQLQIKR IMDKIEDCLT GQDEKILVIL KLDADWVSRW KETKNAFSMF
GCIAGALMLT FKDKIARAKE YCWPLREPID YSLLGFYHDT ALELTKNHML EDNPKIYLDI
LDKCKHHEFC MKIFIHALHA NPKRSNEELS KLHKALQPVH QASHTSAHNS LDSNIIAKKM
FMFSYSDLPK EYRSCLLYLA IFPRRQHIRR STLIGRWVVE GLITKQDWAS SVRHANRCFE
ALINRWLLYP ADIGATGQVK SCVIGDVVHG FITKIARKQR IVETRLSHYL ARHFSIFNNL
RIRRSDTINR FFEKLYEESF RVSIIKVLDL EGCKCFGGKN QRYLKDICRT MLLLKYLSLR
KTDVKQLPSE INNLRELEVL DIRDTDVPES ATVNVLLLKL KHLLAGHVVL NSVPCVPDKI
GKMLNMEVLS NVKARNHQVL KDIGKLWQLR KLGVVIEDND KLVRNLLRAI SDLHECLKSL
SITLPMTDQD PSTEDFPIDV LEYYKHPPKL LESLSITGTT KNRQLLQLLT KDNDFFQLAK
ITLTGTRLKQ DNLKVLNQLP NIVCLRLREK AYIDDNLTFK NEEFKNLKCF LVEGSNMTDI
LFEGGAHKLE KIILCSTDGI QSLSGVEALP ELKEVKLNNN NNKLSLFDKA EKVSKVTLCS
TKLSEDDLKM FAKIRYVRCL ILKEKACVES QIKFNKDEFP SLNLLIVDGS AITNIGFANG
SAPKLEKIIW SFTEDKVRSL SGIDNLPKLK ELEFNGDLIP GELKEAINKH KNKPNLIHNK
PENQYQEMGN IKEMGKAARF PSCWKSQD
//
