ID A0A3B6RCU0_WHEAT Unreviewed; 1307 AA.
AC A0A3B6RCU0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Enhancer of mRNA-decapping protein 4 WD40 repeat region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_097235 {ECO:0000313|EMBL:KAF7094975.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7A02G220400.4};
RN [1] {ECO:0000313|EMBL:KAF7094975.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7094975.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7A02G220400.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7A02G220400.4};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7A02G220400.4}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7094975.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7094975.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the WD repeat EDC4 family.
CC {ECO:0000256|ARBA:ARBA00009639}.
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DR EMBL; CM022229; KAF7094975.1; -; Genomic_DNA.
DR STRING; 4565.A0A3B6RCU0; -.
DR EnsemblPlants; TraesCS7A02G220400.4; TraesCS7A02G220400.4; TraesCS7A02G220400.
DR Gramene; TraesCS7A02G220400.4; TraesCS7A02G220400.4; TraesCS7A02G220400.
DR Gramene; TraesCS7A03G0513500.1; TraesCS7A03G0513500.1.CDS; TraesCS7A03G0513500.
DR Gramene; TraesRN7A0100484900.2; TraesRN7A0100484900.2; TraesRN7A0100484900.
DR OMA; WASTNDE; -.
DR Proteomes; UP000019116; Chromosome 7A.
DR Proteomes; UP000815260; Chromosome 7A.
DR GO; GO:0000932; C:P-body; IBA:GO_Central.
DR GO; GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IBA:GO_Central.
DR Gene3D; 1.10.220.100; conserved c-terminal region of ge- 1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR045152; EDC4-like.
DR InterPro; IPR049404; EDC4_C.
DR InterPro; IPR044938; EDC4_C_sf.
DR InterPro; IPR032401; EDC4_WD40.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15598; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR PANTHER; PTHR15598:SF8; OS06G0300800 PROTEIN; 1.
DR Pfam; PF21289; EDC4_C; 1.
DR Pfam; PF16529; Ge1_WD40; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 194..506
FT /note="Enhancer of mRNA-decapping protein 4 WD40 repeat
FT region"
FT /evidence="ECO:0000259|Pfam:PF16529"
FT REPEAT 241..283
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 360..393
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1175..1279
FT /note="Enhancer of mRNA-decapping protein 4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21289"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 593..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 768..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..63
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..629
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 643..665
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..819
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 820..838
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 851..878
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1307 AA; 141887 MW; CC8030ECCD69311D CRC64;
MASPSGNPNP NPNVPFELSR LFKPPPNPNH PTTVPTPAGI FPGGPPGAPM ATGPPGPYSY
PPATPPFHRN PYLNYPTDPN AVHLPVAAFA NPNPTGNPIP NSNPGPNPGA RLMQLLGNTA
PTHLESVVSM PPTSSEFSGG PVAPLPGMPS APPARMTSTS SKMPRGRLLG PGDRAVHDVD
SRLPGEAQPP QLEVTPITKY TSDPGLVLGR QIAVNRTYIV YGLKLGNIRV LNINTALRSL
LRGHTQRVTD MAFFAEDVHR LASASVDGRI YVWKIDEGPD EENKPQITGK IEMAIQIVGD
AGTYHPRICW HSHKQEILFV GIGNCVLKID TTKVGRGRDF SKEEPLKCSL DKLIDGVHLV
GKHDGDVTDL SLSQWMTTRL ASASKDGTVK IWDDRRTVPL SVMKPHDGKA VYSVSFLTAP
EQPNHINLVT AGPLNREVKI WASSDKEGWL LPSESETWRC TQTLELVSSL ENRFEEAFFN
QVAVLPQASL ILLANAKKNA IYAIHVEYGP DPASTRLDYI ADFTVAMPIL SLTGTHESQP
DGEHVVQVYC VQTMAIQQYG LELLLCLPPT ADNAGLGRDL AISHAYERPL EVASVESSTE
TKPLSDHQGT ADTATHVSSP TPSSNMDNAG SYAEAVLRRE ASRGPSLGDH DGDKSSFDYS
KKRMDSDGTS GQGAFDRKDC FGNEEPRGGQ VDGTVSDPHP TFKVGVNATH LITPSEIISG
VLPSAESTAN GSPQNVEMES KLVAEKKADQ NIGFEDVKET QIVQEKMERL NMSSEQTVET
ISERSVTTDK YSVEDSQRSD PTLLKQHSGA RDENLPRRTA EATENINGSS SRNLQLPSAT
KEEKVLHPQV SGQMSPLTST FNSTDSSHEH PSNTNPAIDS VPQVAAIQGT LQQLMAMHTD
MQKQLNAIVS APIAKEGKRI ETSLGRNIEK SIKANVDAMW ARIQEENARH EKVERERMQQ
ISTLITTSVN KDIPAILEKS LKREISLLGP TIARTTTPII EKSLSSAVSD SLQKVLGEKV
ANQLDKSIST KLEATVAKQI QTQFHTSAKQ ALQDALRSSF ESSIIPAFEQ SCKTMFEQVD
GAFQKGMSEH GTAIQQQVAA AHSPLAQTLR ETINSASSIT QGLTSELLDG QRKLLALVAS
GNPISHNTSA LQPINGPIPN LPEADVPLDP MKELTRLLSE QKFDEAFTMA LQRSDVSMVS
WLCSQVDLQG LCRLNPVPLN QGVLLALFQQ LACDIANDTP LKLQWMTAVA MAIQPTHQMI
AAHVRPIFEQ VYGVLARQQS VPGTSPLEAN NIRLMMHVIN SVMMTHK
//
