ID A0A3B6RHC1_WHEAT Unreviewed; 895 AA.
AC A0A3B6RHC1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=CFC21_098481 {ECO:0000313|EMBL:KAF7096552.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7A02G341200.1};
RN [1] {ECO:0000313|EMBL:KAF7096552.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7096552.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7A02G341200.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7A02G341200.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7A02G341200.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7096552.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7096552.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; CM022229; KAF7096552.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6RHC1; -.
DR SMR; A0A3B6RHC1; -.
DR STRING; 4565.A0A3B6RHC1; -.
DR EnsemblPlants; TraesCS7A02G341200.1; TraesCS7A02G341200.1; TraesCS7A02G341200.
DR Gramene; TraesCAD_scaffold_042867_01G000200.1; TraesCAD_scaffold_042867_01G000200.1; TraesCAD_scaffold_042867_01G000200.
DR Gramene; TraesCLE_scaffold_032624_01G000200.1; TraesCLE_scaffold_032624_01G000200.1; TraesCLE_scaffold_032624_01G000200.
DR Gramene; TraesCS7A02G341200.1; TraesCS7A02G341200.1; TraesCS7A02G341200.
DR Gramene; TraesCS7A03G0840100.1; TraesCS7A03G0840100.1.CDS; TraesCS7A03G0840100.
DR Gramene; TraesWEE_scaffold_033369_01G000200.1; TraesWEE_scaffold_033369_01G000200.1; TraesWEE_scaffold_033369_01G000200.
DR OMA; YFASHAQ; -.
DR Proteomes; UP000019116; Chromosome 7A.
DR Proteomes; UP000815260; Chromosome 7A.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 3.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF449; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..895
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039994778"
FT TRANSMEM 584..602
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 822..846
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 456..801
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DISULFID 749..805
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 895 AA; 100413 MW; ECE5926AE67BB539 CRC64;
MMDTAARARI TSWCSLLLFL GLSFAQNAAE GEAGTLDVGV ILNMRSLLGK MSRTSILMAM
EDFYAVHHSD HATRLVLHVR DSNGGGNIQA ASAAIDLLEN HHVQAIIGPE KSAEATFVSD
IGNNSQVPVI SLQQRTPPFH LPIDAAQVNS IAALIKAFGW REVVPIYEDT DYGRGIIPYL
VDALQEFGAS MPYRSVISQS ASSDQVEQEL YKLMTMQTRV YIVHMLPTTG SILFKKAKEI
GMMTEAYVWI LTDGIANIVN SLSPSVLDAM DGALGVRFHV PRSKALNDFT ARWNKRYKQE
YPDDSLSQLS IYGLWGYDAV WALALAAAKV RMTRPTFQKQ QKYRKNSTFV GTLGVSTVGP
KLLDAILQCK FRGLSGDFDL RNRQLQFSTF QIINVVRRES KEIGYWTAKQ GIFRNLNQDV
SAHTYLHPMP DLNPVVWPGQ THIVPKGWQI PTNGKKLRVG VRTSGYSEFM KVERDPVTNA
ITATGYAIDV FEEAIKKLPY AVPYEYVSFD ALGVNYRSYN DFVYQVPLGV YDAAIGDITI
RHNRTSYADF TLPYTESGIA MIVPVKDNTN KNTWIFLKPL TGDLWFASIA FLIYTGIVIW
LLERRIRNAE LTGSFFRQLG IAIYFSFFAD RERIESILSR LVVVVWVFVL LVITSSYTAN
LSSMLTVQKL QPTETDVHEL LKRGEYMGYR TSSYVRELLE QLGFERSKIR AYNNPDDFAD
ALNKGSKNGG IAAAIHEVPY IKLFLAKHCK GYTMVGPIYK SEGFGFAFPK RSPLVDDFSR
AILKITEGDA IIQIEKKWIG DEHACKNDET IISPSSLNFK SFSGLFLVTG VASTSALLVT
LVMFLYKNKH KMGIKIGRDQ VQRGHGKTRR RIQESATDSD ILRRMIQLTT PASKR
//
