ID A0A3B6RIN3_WHEAT Unreviewed; 681 AA.
AC A0A3B6RIN3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7A02G376500.2};
RN [1] {ECO:0000313|EnsemblPlants:TraesCS7A02G376500.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7A02G376500.2};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7A02G376500.2}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- SIMILARITY: Belongs to the phospholipase D family. C2-PLD subfamily.
CC {ECO:0000256|ARBA:ARBA00010683}.
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DR AlphaFoldDB; A0A3B6RIN3; -.
DR EnsemblPlants; TraesCS7A02G376500.2; TraesCS7A02G376500.2; TraesCS7A02G376500.
DR Gramene; TraesCS7A02G376500.2; TraesCS7A02G376500.2; TraesCS7A02G376500.
DR Gramene; TraesCS7A03G0916400.1; TraesCS7A03G0916400.1.CDS; TraesCS7A03G0916400.
DR Proteomes; UP000019116; Chromosome 7A.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0070290; F:N-acylphosphatidylethanolamine-specific phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0004630; F:phospholipase D activity; IEA:UniProtKB-EC.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR CDD; cd04015; C2_plant_PLD; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR InterPro; IPR015679; PLipase_D_fam.
DR PANTHER; PTHR18896; PHOSPHOLIPASE D; 1.
DR PANTHER; PTHR18896:SF59; PHOSPHOLIPASE D ALPHA 2; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF00614; PLDc; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50035; PLD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022963};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 1..132
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 335..374
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 681 AA; 76441 MW; B1C8DA2F06556BD8 CRC64;
MAHRLLHGTL HATILEADNL TNPDRATGGA PQIFRRFVEG FEETIGRGKG STQLYATVDL
GKARVGRTRV IAGDPVNPRW YEEFHIYCAH FAADVVFTVK AAQPIGATLI GRAYLPVREL
LDAGGREIER RLDVLDPSKK KIHHGPTIHV RLRFCDVAAN PREWGAGLGG ARHPGVPYTF
FSQRPGCRVT LYQDAHTPDA FAPRIPLSGG RTYQQGRCWE DVFDAISDAR HLIYVTGWSV
YTEITLIRDG SRPRPGGDAT LGELLKRKAS EGVRVLMLVW DDRTSVESLG MTWGYMGTHD
AETAEYFRGT DVQCVLCPRN PDIGRSAVMG LQTAYMISHH QKIIAVDHDM PVRGSLSRRR
IVSFVGGLDL CDGRYDTQFH SLFRTMDTAH HKDFHQPNFV DTSITKGGPR EPWHDIHAKI
EGPAAWDILY NFEQRWRKQG GDNDLLVDLR ALANLIIPPS TVTFPDDQEA WNVQVFRSID
GGASFGFPNT PEQAARSGLV SGKNNTLDRS IQDAYIHAIR RAQHFIYIEN QYFLGSSFAW
KADDIRPEEI EALHLIPREL SLKIVSKIEA GEHFVVYVVV PMWPEGAPEG GSVQAILDWQ
RRTMDMMYYD ISIALKAKGI DASPKDYLTF FCLGNREAKR SGEYEPADHP LPGSGYEKAQ
NARRFMIYVH SKMMIVCLIS S
//
