ID A0A3B6RJ53_WHEAT Unreviewed; 419 AA.
AC A0A3B6RJ53;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN ORFNames=CFC21_098958 {ECO:0000313|EMBL:KAF7097102.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7A02G389600.1};
RN [1] {ECO:0000313|EMBL:KAF7097102.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7097102.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7A02G389600.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7A02G389600.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7A02G389600.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7097102.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7097102.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR EMBL; CM022229; KAF7097102.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6RJ53; -.
DR SMR; A0A3B6RJ53; -.
DR STRING; 4565.A0A3B6RJ53; -.
DR PaxDb; 4565-Traes_7AL_33F0E8FBE-1; -.
DR EnsemblPlants; TraesCS7A02G389600.1; TraesCS7A02G389600.1; TraesCS7A02G389600.
DR Gramene; TraesCAD_scaffold_082172_01G000300.1; TraesCAD_scaffold_082172_01G000300.1; TraesCAD_scaffold_082172_01G000300.
DR Gramene; TraesCLE_scaffold_018481_01G000100.1; TraesCLE_scaffold_018481_01G000100.1; TraesCLE_scaffold_018481_01G000100.
DR Gramene; TraesCS7A02G389600.1; TraesCS7A02G389600.1; TraesCS7A02G389600.
DR Gramene; TraesCS7A03G0942700.1; TraesCS7A03G0942700.1.CDS; TraesCS7A03G0942700.
DR Gramene; TraesKAR7A01G0343710.2; cds.TraesKAR7A01G0343710.2; TraesKAR7A01G0343710.
DR Gramene; TraesROB_scaffold_030994_01G000100.1; TraesROB_scaffold_030994_01G000100.1; TraesROB_scaffold_030994_01G000100.
DR Gramene; TraesWEE_scaffold_088844_01G000200.1; TraesWEE_scaffold_088844_01G000200.1; TraesWEE_scaffold_088844_01G000200.
DR OMA; PEQFMNI; -.
DR OrthoDB; 1214460at2759; -.
DR Proteomes; UP000019116; Chromosome 7A.
DR Proteomes; UP000815260; Chromosome 7A.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR022742; Hydrolase_4.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005:SF164; LIPASE; 1.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR Pfam; PF12146; Hydrolase_4; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid degradation {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid metabolism {ECO:0000256|PIRNR:PIRNR000862};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..419
FT /note="Lipase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039994795"
FT DOMAIN 58..114
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT DOMAIN 119..237
FT /note="Serine aminopeptidase S33"
FT /evidence="ECO:0000259|Pfam:PF12146"
FT ACT_SITE 191
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 361
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 395
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ SEQUENCE 419 AA; 47128 MW; BEC54708198CAB07 CRC64;
MILHHLMARN LFVVSLLILS LVFNSCTAHS WRNNSSLDDV GPRCEPSSHP FGLCKTRAAA
FGYPCEDHMV TTEDGYILSL KRIPHGVSNS TQNTTRIPVL LFHGLMVDSV SWVLGTPKQS
LGFILADGGF DVWFANTRGT NSSRNHTSLT PDDPEYWNWT WDQLAAYDLP AVLQHVYDHT
GGQKVHYIGH SLGTLIILAA FSEHRLLHLV RSAVLLCPIA YLYKTKSKLT RLATQILLAE
AFHFLGYREF NPVGPVSHEI LLIICGDPEI DCYDLFTAVM GPDCCLNAST VCNFLQHATQ
STSIKNLIHM SQMIRYEGVR RYDYGNAKEN MKHYSQPSPP LYNLSSIPTH VPMFLTHGGQ
DFLGDVPDTR HLLKTLVRTH DSDNMEVLYV PDYAHADFVI GYNAPQLVYG PMVDFLQRH
//
