ID A0A3B6RJ73_WHEAT Unreviewed; 979 AA.
AC A0A3B6RJ73;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=USP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_097850 {ECO:0000313|EMBL:KAF7095748.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7A02G282200.5};
RN [1] {ECO:0000313|EMBL:KAF7095748.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7095748.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7A02G282200.5}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7A02G282200.5};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7A02G282200.5}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7095748.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7095748.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C19 family.
CC {ECO:0000256|ARBA:ARBA00009085}.
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DR EMBL; CM022229; KAF7095748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6RJ73; -.
DR EnsemblPlants; TraesCS7A02G282200.5; TraesCS7A02G282200.5; TraesCS7A02G282200.
DR Gramene; TraesCS7A02G282200.5; TraesCS7A02G282200.5; TraesCS7A02G282200.
DR Gramene; TraesCS7A03G0660700.4; TraesCS7A03G0660700.4.CDS; TraesCS7A03G0660700.
DR Proteomes; UP000019116; Chromosome 7A.
DR Proteomes; UP000815260; Chromosome 7A.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02661; Peptidase_C19E; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF874; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 116..153
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT DOMAIN 454..759
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 200..241
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 778..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 820..870
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 950..979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 35..62
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 832..870
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 952..968
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 979 AA; 107906 MW; 8F1C0A2A51B534E7 CRC64;
MAMAEAAGSS TAATAVTVAL FIVVLVVALL LRQSLRRAAE RREEVRRLAR LAAEESELAE
RESVLAFCSE LFPGVLHAAD VPEAPMWAPR EVVSPQEEEE EVVEAPAPPQ AAAGVCAVCF
RPTTFRCKQC KAVKYCSFKC QISHWRKGHK DECHPPSANA KPDDGAAISV AKEGNVEHRR
ASEENVVAGV QPVAEISVPV ASESETSGTN HVVKSSNDKR KDTPFEEVSA TTEIPEKGNS
DNVVKLGQIT PQVTSFDSKR AESNTKSTNF VGNSSYVKDL DDILVHKSQA SAPKMSGLTS
SIHEDIYVHC KDHGNTEDAD VSKDCSRINH IRKPADRSYS QMAATAVPAP KSSRTSLRVE
VEPCKIKATG EEKSEGLKLV TPVLAVDKVS SIHGGRSVAP NPSKRADNPT DRGGSAANNL
ATSLKKIVRQ QTTPKVVRHY PSELLYDKVE LRPFGLHNLG NSCYANVVLQ CLMFTRPLTT
YLLGGLHSKN CSKKAWCFMC EFERLIVEGK QGKTALSPTG ILSHLHEIGS SFGPGKQEDA
HEFLRHSIDA MQSVCIKEAR KGGAHCLAEE TTLVQLIFGG YLRSKIKCTR CHISSEQYER
MLDLTVEIDG DISSLEEALQ RFTSTEVLDG DNRYQCSRCN SYERAKKKLT ISEAPNVLTI
ALKRYQSGKF GKISKAIRFP ETLNLSCYMN STDDNSPVYS LYGMVVHHDV MNAAFSGHYV
CYVKDTHGKW YKIDDSQVKP VSLENVMSKC AYMLLYARCS PRAPNSVRHA MMVNDPSYAK
KARHKPNLEQ APLQRGSLNR HQGDELHRDH ITDNLTRRFD EFGDAPYPAA ESPSPSESSS
LFSNSDAGSH STVSTDSSES TRNSTSTDDY EQYFFGSSDQ MYQGGPRGAH EEIGYTSYYR
SRSALGTSSS GQEVDEERSV EQRFEVSGSS PLSYTDQSKQ HLLTEQYRQF GGSEHDPGEA
RGSVLLRRSA REKTAQTFY
//
