ID A0A3B6RQD8_WHEAT Unreviewed; 875 AA.
AC A0A3B6RQD8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7099156.1, ECO:0000313|EnsemblPlants:TraesCS7A02G562000.1};
GN ORFNames=CFC21_100831 {ECO:0000313|EMBL:KAF7099156.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7A02G562000.1};
RN [1] {ECO:0000313|EMBL:KAF7099156.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7099156.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7A02G562000.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7A02G562000.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7A02G562000.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7099156.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7099156.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022229; KAF7099156.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6RQD8; -.
DR SMR; A0A3B6RQD8; -.
DR STRING; 4565.A0A3B6RQD8; -.
DR PaxDb; 4565-Traes_7AL_95CF63943-1; -.
DR EnsemblPlants; TraesCS7A02G562000.1; TraesCS7A02G562000.1; TraesCS7A02G562000.
DR Gramene; TraesCS7A02G562000.1; TraesCS7A02G562000.1; TraesCS7A02G562000.
DR Gramene; TraesCS7A03G1370400.1; TraesCS7A03G1370400.1.CDS; TraesCS7A03G1370400.
DR Gramene; TraesPAR_scaffold_008570_01G000300.1; TraesPAR_scaffold_008570_01G000300.1; TraesPAR_scaffold_008570_01G000300.
DR OMA; LIGDEYP; -.
DR Proteomes; UP000019116; Chromosome 7A.
DR Proteomes; UP000815260; Chromosome 7A.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF968; NB-ARC DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 5..92
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 175..400
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 875 AA; 98973 MW; 6047F853E38879C3 CRC64;
MAESAIGSVL GNVSTLAVQE TTFLCGVNLE VGFLKDELKR LKSYLKSADA KRRSGDELVA
TWVSQIRDAA YEAENAIEAA DYTEKRNRLK NGFMGAISRY ARLPSDLIAL HTIGAEIQRV
KRKISEIFDS ANRLKINLDT SDVEKVLIGD EYPQDYGTMH QNFEDIDLIG FGDEYKEIVG
KLVDKENITL SVVSIVAMGG AGKTTLARKV YTSSSVKQHF EATSWVTVSQ KFKGIDLLKD
IMKQIMGGRD ESIAKMNEYE VGKEIHDFLL HKRYLIVLDD VWETDTWDQI NKRVKAFPDA
TNGSRVLLTT RKGDVANHVQ MPTLVHHLKK LDEEKSWELF SSKALPPYKR SAIRDVDEFK
KLGKRLAKKC DGLPLALAVL GGYLSKNLNA QTWSNILSDW PATKDGKMMR VILARSYKDL
PNHLRSCLLY FAAFPEDYEI YVAYLIELWI AESFIPHTPN HTLEETAQRY VTELAQRSLV
QVVRRSRAHG WIERIRIHDI LHDWCIEEAR QDGFLDAIDK TAGQAGASSS SDNLMSYRFS
FQTLSDQILP ATPNVRSLLG FGLSSTSLPK LRFLRVLCIE DSTLKDFSSV IGRCIHLRLL
RLRYCEGVAL PSSIGKLLYL QTIDLRGTIL ESVVPNSLWD IPTLRHVYLR NCFFSPPPPA
RSVRLQPKEL QSFALLLDPV GTDFRCHDMM IFLGQLNQLT TFCLFMHPNI PAEVLNIFAN
MPHLVDISLG QFDVLDKLPA EFPQSVRSLF LSADVIKQDP MPILEKLPCL VVLRLWGYKG
QTMCCSSQGF PRLQELLLGS FSTEVWRMEE GAMPKLSHLT LQSCKKISKL PVGLLHLPSL
DHLELAFMTQ ISEDDITLNE LRRKGCEVHT YVRAA
//
