ID A0A3B6SIC7_WHEAT Unreviewed; 1716 AA.
AC A0A3B6SIC7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_104690 {ECO:0000313|EMBL:KAF7103730.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7B02G353800.1};
RN [1] {ECO:0000313|EMBL:KAF7103730.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7103730.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7B02G353800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7B02G353800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7B02G353800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7103730.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7103730.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022230; KAF7103730.1; -; Genomic_DNA.
DR EnsemblPlants; TraesCS7B02G353800.1; TraesCS7B02G353800.1; TraesCS7B02G353800.
DR Gramene; TraesCS7B02G353800.1; TraesCS7B02G353800.1; TraesCS7B02G353800.
DR Gramene; TraesCS7B03G0947800.1; TraesCS7B03G0947800.1.CDS; TraesCS7B03G0947800.
DR OrthoDB; 5513449at2759; -.
DR Proteomes; UP000019116; Chromosome 7B.
DR Proteomes; UP000815260; Chromosome 7B.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008962; PapD-like_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45707; C2 CALCIUM/LIPID-BINDING PLANT PHOSPHORIBOSYLTRANSFERASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR45707:SF76; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50202; MSP; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 32..303
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 322..439
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
FT REGION 1490..1524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 59
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1716 AA; 194181 MW; C0CE7B36A9C9178D CRC64;
MGDANVLERI LDGAADPTNL SLQLLKDITG NFSQDRKIGQ GGFGEVYKGV LGEKIVAVKR
IHINENTVDD GLFRREFGSL SKTNHRNVVR FLGVCSNTLQ KTIEDAWSGE IRLASVLERL
LCFEYISNGS LDKHITDELR GLEWETRYEI ITGICKGLRY LHKEKDIIHM DLKPANILLH
HQDGKYMIPK ITDFGLARPN KNSHTVGQCY GTPGYWAPEC RDDSKTTTAC DIYSLGAIII
ELVTGCKDIP DKNYVLRRWR HRWNNPPTQL QYQQVTRCID IAVRCREKNP ESRPSISEII
NFLSESEETC GQIIPCLDED DMLRINPLEL RLPSELKNEI SCKVEPRNGT RNCIAFNIQL
PSAQYSAQPV KCIVQPRSMY VVMITVQARD VREHDHADKL IVESMKWTEG LGQEDIIECM
SGAEKRKEVD EVDLIVVYET TKPQENCKRR RETNMPGDED PKARKIKIVE SASCSGENKE
APSMDINSST RGQCTGKTEQ CKLYPLQSFS RHSATNEKYL GKKSHRAVDV SRGAMGSLLD
KLGKLVTEDY SLDPSIKSDI ESFSSELEIM HQDLPKLENI DNAKIWVDKV RELSYYIEDM
VDTFLVHVEL DSSRCGFREL TCKGLKLLVN GMTTHDHTDD VIKDIKVKVK AVADGKGKYN
IDVNNVVANA IEKAAIYPRM AVYTNKEHLI GIETPRDDVI GLFEEGGDVD KQELRIVSIV
GMGGLGKTTL AKAVYEEFKG YSHKAFVSVG QNPDLVNVLK KTIRDCQGRE YNAAKLEQLD
VEQLCNELRN FLKDKRYFIV IDDLWGCPLW DTINSAFPRD KCGSRVITTT RIQEVVDRES
WNVENKVYRI KPLSHKDSRS LFFRRISDPR KDCPVTPRKE EILADILRRC GGMPLAINSI
ASHLARHSSE SSWEHVRKSL GATQCNDVEQ MKKILDLSYI HLPDHLKTCL LYVCMYSEDR
KINKNDLLRQ WVAEGFVSTD GGQDAEDVAE EYFKALIDMF MIQPWKIDYC TNEVLSCRVH
DIILELMRSK SSEEKFIHVI DGLKDVSGQI HRVSVQYNDK EDSRTLKTIK GSLSHARSVL
LYRASLLPAF LEFKHVRVLH LEDKVYSREP LDLTGISSLF FLRYLKIALH PLSGDLKLPD
QLGQLQQLET IHLKGGGLKK YPSDLCTLPR LSCLIYSRYG GIMLPYGIER LKSLHILKGV
CLYKSSVETI KGLGELTNLR NLGINSNFPI GWGFHESEEV AYARMNALHS SISSLSTSVR
ILTLHAYLPG HDMEYWNRTL FPQGSHIRKL HLSGCSFYTC PEWIGQLHDL YSLTITVMEV
ADSISIVEGL TSLAYFELST DTDRYWKEKE SIVISGGGAF QALKHLIFHC PKVSLIFEVG
ALPKLEKLEI LFCHLTHHIS YLAVGIEHLP APTLEQIIIK LTRNIKSGFS ITINDWDDND
WECDYASDQE TDSLIKQLRK LRSVLKRAFK KHHPGADIYI EFEDYSYDPS QQKERYRSDE
EAESVDDEDD EGAHQVNGSQ TAAQVQTNTR QLIELIDAQE DSARMSINID APLMVGTSID
LAVGLEGWQG GRGSQDLAVL ESSEQPSTSL LAPLPSSIPL FAWADTAEPM ANFSVDININ
NDLLVQQGND GMLVNTVGQY LDLNQQAHAR ELFDLNHASS ADSESLQLPF RSLLAPSSSS
LHHTLELSLW PDAAETERDY LNPAPNEITD EEFFVD
//
