ID A0A3B6SQJ0_WHEAT Unreviewed; 947 AA.
AC A0A3B6SQJ0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=NB-ARC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_104664 {ECO:0000313|EMBL:KAF7103701.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7B02G351100.1};
RN [1] {ECO:0000313|EMBL:KAF7103701.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7103701.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7B02G351100.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7B02G351100.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7B02G351100.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7103701.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7103701.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; CM022230; KAF7103701.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6SQJ0; -.
DR STRING; 4565.A0A3B6SQJ0; -.
DR EnsemblPlants; TraesCS7B02G351100.1; TraesCS7B02G351100.1; TraesCS7B02G351100.
DR Gramene; TraesCAD_scaffold_020918_01G000100.1; TraesCAD_scaffold_020918_01G000100.1; TraesCAD_scaffold_020918_01G000100.
DR Gramene; TraesCLE_scaffold_047447_01G000100.1; TraesCLE_scaffold_047447_01G000100.1; TraesCLE_scaffold_047447_01G000100.
DR Gramene; TraesCS7B02G351100.1; TraesCS7B02G351100.1; TraesCS7B02G351100.
DR Gramene; TraesCS7B03G0940600.1; TraesCS7B03G0940600.1.CDS; TraesCS7B03G0940600.
DR Gramene; TraesKAR7B01G0398880.1; cds.TraesKAR7B01G0398880.1; TraesKAR7B01G0398880.
DR Gramene; TraesPAR_scaffold_058955_01G000300.1; TraesPAR_scaffold_058955_01G000300.1; TraesPAR_scaffold_058955_01G000300.
DR OrthoDB; 418633at2759; -.
DR Proteomes; UP000019116; Chromosome 7B.
DR Proteomes; UP000815260; Chromosome 7B.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1208; DISEASE RESISTANCE PROTEIN RPM1; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 5..89
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 174..406
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 947 AA; 105492 MW; 7711AB8923270833 CRC64;
MAEAVMGPLL GALQELVMKE AQAMAAVDDD VRNLRDKLMW LQAFLRDAEP RRRARNDELT
RVCLHQIRGA VFDAEDAVDR YFLKIDLSKY PGWSQAVVQF FIGLTTQVRV RRDLSRRVGS
INKRLERIIE NKDKYKIDNQ DSSSVTTWRP STDISAAIEN LGRFTLPLVG RDEKQEEMRK
VLNEESKHPM VITLAGESGL GKTKLTKAIY EDPVTKEHFR VRVWVSFAPG LSASQILKLV
LLRLALKPTK SSYDGDDDPG VRLQAALRAK IYLLVLDGEV SSTEWNGILS ILGRTSSAKS
RVVRITRTDP VAQSSNFVDR NILLTHLDKG TSVELFRKAL LWGRGGEKYN RISADDLEMK
KHLDSIHDVT GGLPLSVVLL AGLLQTKEFP GEWTRVFEHL TDKSGKSKRD DIILSMCFDD
LPHDLKSCFL YLACFPVNML VKARTMVCMW MAEGFLSPRG GMTMEKVGSH FLNELAQRHL
INIPPVEYAD PGFESVTVQS RVHDFLLHEA QEVHGGDDVP MLTTTRRLAL QNHSDKYAAL
ATPLPKLRSI FSSFEKEDTG MGTATAAAHA AGDRNKKGTN TTIARVFPHL LRSPGSAYTD
PKTIIQRLLC NSKFLRVISL DGLDIGIELP HEIGSVVHLQ HLAITSCSLK VIPPSIGKLT
RLQTLDVRGT GVNALPMGFW KIRTLRHVFG SILLPRRVGN LEQLRNLTTV NHGNNGAWDE
KTFSRMVRLN MLHVDGISAS NVEAIYKLKY LVILNLASGD QAVIPSDLFT RSNLPRLQMM
RLAGKMEQSP TLSGRNFTLP TLTQLFLKNT MVPQSFINQL GIGLPLLSVL VLLEGACESE
SIVFSTGFHS IKYVTLDVEL LRVEIQSPAF GHNLVQVEIV TYSPEILVDI SQKPDIKDKI
KIDDKYIRGM ADPAPEVPNG ALQALLNHLM AATGGARPIA SRIQTKP
//
