ID A0A3B6SQT2_WHEAT Unreviewed; 386 AA.
AC A0A3B6SQT2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7105505.1, ECO:0000313|EnsemblPlants:TraesCS7B02G485300.1};
GN ORFNames=CFC21_106312 {ECO:0000313|EMBL:KAF7105505.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7B02G485300.1};
RN [1] {ECO:0000313|EMBL:KAF7105505.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7105505.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7B02G485300.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7B02G485300.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7B02G485300.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7105505.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7105505.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C1 family.
CC {ECO:0000256|ARBA:ARBA00008455}.
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DR EMBL; CM022230; KAF7105505.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6SQT2; -.
DR SMR; A0A3B6SQT2; -.
DR STRING; 4565.A0A3B6SQT2; -.
DR EnsemblPlants; TraesCS7B02G485300.1; TraesCS7B02G485300.1; TraesCS7B02G485300.
DR Gramene; TraesCS7B02G485300.1; TraesCS7B02G485300.1; TraesCS7B02G485300.
DR Gramene; TraesCS7B03G1310400.1; TraesCS7B03G1310400.1.CDS; TraesCS7B03G1310400.
DR OMA; SCWAFMS; -.
DR Proteomes; UP000019116; Chromosome 7B.
DR Proteomes; UP000815260; Chromosome 7B.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IBA:GO_Central.
DR CDD; cd02248; Peptidase_C1A; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR025661; Pept_asp_AS.
DR InterPro; IPR013128; Peptidase_C1A.
DR InterPro; IPR000668; Peptidase_C1A_C.
DR InterPro; IPR039417; Peptidase_C1A_papain-like.
DR InterPro; IPR013201; Prot_inhib_I29.
DR PANTHER; PTHR12411; CYSTEINE PROTEASE FAMILY C1-RELATED; 1.
DR PANTHER; PTHR12411:SF803; OS04G0107700 PROTEIN; 1.
DR Pfam; PF08246; Inhibitor_I29; 1.
DR Pfam; PF00112; Peptidase_C1; 1.
DR PRINTS; PR00705; PAPAIN.
DR SMART; SM00848; Inhibitor_I29; 1.
DR SMART; SM00645; Pept_C1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00640; THIOL_PROTEASE_ASN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..386
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040072757"
FT DOMAIN 52..109
FT /note="Cathepsin propeptide inhibitor"
FT /evidence="ECO:0000259|SMART:SM00848"
FT DOMAIN 161..385
FT /note="Peptidase C1A papain C-terminal"
FT /evidence="ECO:0000259|SMART:SM00645"
SQ SEQUENCE 386 AA; 41838 MW; 3E5B234EE3C1D317 CRC64;
MAFMRSSSSS MALALLPLLV AAAFFIPSMA SSASGTLDHG LDGEALLMLG RFHGWMAAHG
RSYATVEEKL RRFEVYRSNM EFIEAANRDS RMSYSLGETP FTDLTHDEFM AMFSSNSGSN
ESSWESEETT VITTRAGPVH EGTAAVEEPP RRTNLNLTAA VPPSVDWREK GVVTAAKYQG
DSCSSCWAFM SVATMESAHA ISTGGSPPVL SEQQLVDCRI NGCGNSWMDK AFEWVIQNGG
ITTEAAYPYT GKVGTCQRAK PVAVRLRGYK KVTPSGNEAA LMAAVAQQPV AASFDYSDPC
FQHYIRGVYN AGCSRSGVYT KGACGTTQNH ALALVGYGTK PDGTKYWIGK NSWTDQWGDK
GFVYFLRDSP PLGLCGIAKY PLYPII
//
