ID A0A3B6STF2_WHEAT Unreviewed; 392 AA.
AC A0A3B6STF2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN ORFNames=CFC21_105763 {ECO:0000313|EMBL:KAF7104904.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7B02G455500.1};
RN [1] {ECO:0000313|EMBL:KAF7104904.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7104904.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7B02G455500.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7B02G455500.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7B02G455500.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7104904.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7104904.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001482};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the PP2C family. {ECO:0000256|ARBA:ARBA00006702,
CC ECO:0000256|RuleBase:RU003465}.
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DR EMBL; CM022230; KAF7104904.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6STF2; -.
DR SMR; A0A3B6STF2; -.
DR STRING; 4565.A0A3B6STF2; -.
DR PaxDb; 4565-Traes_7BL_2DF32901B-1; -.
DR EnsemblPlants; TraesCS7B02G455500.1; TraesCS7B02G455500.1; TraesCS7B02G455500.
DR Gramene; TraesCAD_scaffold_004190_01G001200.1; TraesCAD_scaffold_004190_01G001200.1; TraesCAD_scaffold_004190_01G001200.
DR Gramene; TraesCS7B02G455500.1; TraesCS7B02G455500.1; TraesCS7B02G455500.
DR Gramene; TraesCS7B03G1229000.1; TraesCS7B03G1229000.1.CDS; TraesCS7B03G1229000.
DR Gramene; TraesKAR7B01G0473420.1; cds.TraesKAR7B01G0473420.1; TraesKAR7B01G0473420.
DR Gramene; TraesPAR_scaffold_094134_01G000100.1; TraesPAR_scaffold_094134_01G000100.1; TraesPAR_scaffold_094134_01G000100.
DR Gramene; TraesROB_scaffold_002969_01G000100.1; TraesROB_scaffold_002969_01G000100.1; TraesROB_scaffold_002969_01G000100.
DR Gramene; TraesWEE_scaffold_098286_01G000300.1; TraesWEE_scaffold_098286_01G000300.1; TraesWEE_scaffold_098286_01G000300.
DR OMA; WRPIERY; -.
DR OrthoDB; 999128at2759; -.
DR Proteomes; UP000019116; Chromosome 7B.
DR Proteomes; UP000815260; Chromosome 7B.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IBA:GO_Central.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR000222; PP2C_BS.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR47992:SF260; PROTEIN PHOSPHATASE 2C 60-RELATED; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS01032; PPM_1; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW ECO:0000256|RuleBase:RU003465};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 47..355
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 392 AA; 43543 MW; A57370525263911D CRC64;
MIVTLMNFLR ACWRPSSNRH ARTGSDATGR QDGLLWYKDT GEHVNGDFSM AVVQANNLLE
DQCQIESGPL SFLDSGPYGT FVGVYDGHGG PETACYINDN LFNHLKRFAS EQNSMSADVL
KKAYEATEDG FFSIVTKQWP VKPQIAAVGS CCLVGVICGG MLYVANVGDS RAVLGKHVKA
TGEVLAVQLS AEHNVSIEPV RKELQSMHPE DRHVVVLKHN VWRVKGLIQV CRSIGDAYLK
KQEFNREPLY AKFRLREPFN RPILSSEPSI CVQPIQPQDE FIIFASDGLW EHLTNQEAVD
IVQSSPRSGS ARRLIKSALL EAAKKREMRY SDLKKIDRGV RRHFHDDITV IILYLDSSLV
SRASTHRGPA VSLRGAGVSL RSSTLAPYGS QM
//
