ID A0A3B6T9N7_WHEAT Unreviewed; 318 AA.
AC A0A3B6T9N7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=WAT1-related protein {ECO:0000256|RuleBase:RU363077};
GN ORFNames=CFC21_107431 {ECO:0000313|EMBL:KAF7106712.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7D02G104900.1};
RN [1] {ECO:0000313|EMBL:KAF7106712.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7106712.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7D02G104900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7D02G104900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7D02G104900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7106712.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7106712.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU363077}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU363077}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000256|ARBA:ARBA00007635, ECO:0000256|RuleBase:RU363077}.
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DR EMBL; CM022231; KAF7106712.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6T9N7; -.
DR EnsemblPlants; TraesCS7D02G104900.1; TraesCS7D02G104900.1; TraesCS7D02G104900.
DR Gramene; TraesCAD_scaffold_014454_01G000400.1; TraesCAD_scaffold_014454_01G000400.1; TraesCAD_scaffold_014454_01G000400.
DR Gramene; TraesCLE_scaffold_044576_01G000200.1; TraesCLE_scaffold_044576_01G000200.1; TraesCLE_scaffold_044576_01G000200.
DR Gramene; TraesCS7D02G104900.1; TraesCS7D02G104900.1; TraesCS7D02G104900.
DR Gramene; TraesCS7D03G0239100.1; TraesCS7D03G0239100.1.CDS; TraesCS7D03G0239100.
DR Gramene; TraesKAR7D01G0048820.1; cds.TraesKAR7D01G0048820.1; TraesKAR7D01G0048820.
DR Gramene; TraesPAR_scaffold_014119_01G000400.1; TraesPAR_scaffold_014119_01G000400.1; TraesPAR_scaffold_014119_01G000400.
DR Gramene; TraesRN7D0100245800.1; TraesRN7D0100245800.1; TraesRN7D0100245800.
DR Gramene; TraesROB_scaffold_029081_01G000300.1; TraesROB_scaffold_029081_01G000300.1; TraesROB_scaffold_029081_01G000300.
DR Gramene; TraesWEE_scaffold_004028_01G000400.1; TraesWEE_scaffold_004028_01G000400.1; TraesWEE_scaffold_004028_01G000400.
DR OMA; NSWVMAK; -.
DR Proteomes; UP000019116; Chromosome 7D.
DR Proteomes; UP000815260; Chromosome 7D.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218; WAT1-RELATED PROTEIN; 1.
DR PANTHER; PTHR31218:SF410; WAT1-RELATED PROTEIN; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU363077};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|RuleBase:RU363077};
KW Transmembrane helix {ECO:0000256|RuleBase:RU363077}.
FT TRANSMEM 29..47
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 59..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 87..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 169..188
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 234..253
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT TRANSMEM 291..308
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363077"
FT DOMAIN 10..130
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 170..308
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 318 AA; 35471 MW; 453AB4671562C409 CRC64;
MVLVQLFITG MILLSKVSIG GGMFIFALLA YRSLFGAAFI LPLALIFERG KWREMGWHAT
GWIFLNAFIG YAVPMSLYYY GLSDTTPTYA VIFLNIIPLV TFILSLVFRM ETLQIWSIAG
SMKIVAVVLS VGGTMLISLY KGKTLHLWDP ILKHHHEGQQ TTEVASNHLR GTIFLVGSSI
TLACWYLIQS KVMKVYPYKY WSSMVTCFVG GFQTALVGII LSRDKNKWKL GWDLNLMTIF
YSGALATAGK YSLNSWVMAK RGPAYPPMFS PLSVVFTVLL DSIFIGDEIT VGSLFGTIVV
IVGLYIFLSA KSKEVRDK
//
