ID A0A3B6TH59_WHEAT Unreviewed; 821 AA.
AC A0A3B6TH59;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=DUF4220 domain-containing protein {ECO:0000259|Pfam:PF13968};
GN ORFNames=CFC21_106683 {ECO:0000313|EMBL:KAF7105913.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7D02G033400.1.cds1};
RN [1] {ECO:0000313|EMBL:KAF7105913.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7105913.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7D02G033400.1.cds1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7D02G033400.1.cds1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7D02G033400.1.cds1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7105913.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7105913.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM022231; KAF7105913.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6TH59; -.
DR STRING; 4565.A0A3B6TH59; -.
DR PaxDb; 4565-Traes_7DS_E2925954F-1; -.
DR EnsemblPlants; TraesCS7D02G033400.1; TraesCS7D02G033400.1.cds1; TraesCS7D02G033400.
DR Gramene; TraesCAD_scaffold_093426_01G000300.1; TraesCAD_scaffold_093426_01G000300.1; TraesCAD_scaffold_093426_01G000300.
DR Gramene; TraesCLE_scaffold_055684_01G000400.1; TraesCLE_scaffold_055684_01G000400.1; TraesCLE_scaffold_055684_01G000400.
DR Gramene; TraesCS7D02G033400.1; TraesCS7D02G033400.1.cds1; TraesCS7D02G033400.
DR Gramene; TraesCS7D03G0075700.1; TraesCS7D03G0075700.1.CDS1; TraesCS7D03G0075700.
DR Gramene; TraesPAR_scaffold_043488_01G000300.1; TraesPAR_scaffold_043488_01G000300.1; TraesPAR_scaffold_043488_01G000300.
DR Gramene; TraesROB_scaffold_013250_01G000300.1; TraesROB_scaffold_013250_01G000300.1; TraesROB_scaffold_013250_01G000300.
DR Gramene; TraesWEE_scaffold_042126_01G000400.1; TraesWEE_scaffold_042126_01G000400.1; TraesWEE_scaffold_042126_01G000400.
DR OMA; YIAYPGR; -.
DR Proteomes; UP000019116; Chromosome 7D.
DR Proteomes; UP000815260; Chromosome 7D.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR025315; DUF4220.
DR InterPro; IPR007658; DUF594.
DR PANTHER; PTHR31325:SF209; DUF4220 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR Pfam; PF13968; DUF4220; 1.
DR Pfam; PF04578; DUF594; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 69..485
FT /note="DUF4220"
FT /evidence="ECO:0000259|Pfam:PF13968"
FT REGION 799..821
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 821 AA; 93511 MW; 13831AC094F5F34F CRC64;
MSSAKAKAAA TILLTLEKLF MLDIATHIAS VELWVLVTTV LLVWRFLLDF SGPWFGKPSR
MFTVVTMEIL NQNLVMYTMG LMQLSGARVN DYFQVWAVLL VTLQYSVKIG RPYTRSKQVP
LLDLMSSFWS ANLLRVQTFE LLRIPLWLIW ALNAVRIIVL FVTSSKGETE NQESMRLVSD
YMSYEDHLPA LAAAAGGSDD EQEVSEMAGC KYLVHGEHRV LKEVQEGRRE GRRRLSSCFR
RERIIIESNR SYKIQLDPDG VHKDHLVTVE KLWRDTSKSR LLGGASTADP GNQRKDLCLS
FAMYKLLRRR FYDLPVHELT RPQGKNKIRK LVIDYILKDC ERAFRITGVE LSFLQDLFYS
KHAAVFAGGA MVPLRSLLLS LSLAAATGYI AYPARYIPER MDPADRNRIT HGVFITRLMV
GIIVLKELLE IFLYVLSRWA KVLMLCKYVQ HQCLRRPMVE MAMRFMLFFG SKAKWIQTVS
QQNLLVTFRV LKPAGVLPPL TWRMVLCRGE TVGTTALKDY TKIAILDTLK KLEKEGLALD
NYFSNAFRSN EKVVEWPRNL KVDTHIILVW HIATSLCEIN FFNTVKKLRA VQRPRPFVDG
PNGIRNKRKN YESVWSEQYA TAATLSNYCT YLVSKDLVPD NPIVAGMVLG EVIQEIDHVT
SKFNRQWGRG KLPFIFVYNG LMETVHKPCE NTDHHQSWGW GPDVEPVTPE QVREKEDDGG
LHIGCSITRM GAMLGKHLIK VYEGHAEGLW SDLANFWTGF LLHLAANTRA ATHGRHLAGD
SELITHLWAL VSHAGFRGNA IHGEEGPDQE DIPDINQAAN Q
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