ID A0A3B6THM4_WHEAT Unreviewed; 1035 AA.
AC A0A3B6THM4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Protein kinase domain-containing protein {ECO:0000259|PROSITE:PS50011};
GN ORFNames=CFC21_106359 {ECO:0000313|EMBL:KAF7105568.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7D02G004900.1};
RN [1] {ECO:0000313|EMBL:KAF7105568.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7105568.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7D02G004900.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7D02G004900.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7D02G004900.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7105568.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7105568.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; CM022231; KAF7105568.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6THM4; -.
DR SMR; A0A3B6THM4; -.
DR STRING; 4565.A0A3B6THM4; -.
DR EnsemblPlants; TraesCS7D02G004900.1; TraesCS7D02G004900.1; TraesCS7D02G004900.
DR Gramene; TraesCS7D02G004900.1; TraesCS7D02G004900.1; TraesCS7D02G004900.
DR Gramene; TraesCS7D03G0010500.1; TraesCS7D03G0010500.1.CDS; TraesCS7D03G0010500.
DR OMA; GFCEHPR; -.
DR OrthoDB; 378360at2759; -.
DR Proteomes; UP000019116; Chromosome 7D.
DR Proteomes; UP000815260; Chromosome 7D.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR GO; GO:0009755; P:hormone-mediated signaling pathway; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48053; LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED; 1.
DR PANTHER; PTHR48053:SF123; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 7.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00365; LRR_SD22; 6.
DR SMART; SM00369; LRR_TYP; 11.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1035
FT /note="Protein kinase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040072837"
FT TRANSMEM 688..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 752..1013
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 781
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1035 AA; 113632 MW; A18FE7DE76773049 CRC64;
METERPKVLA SLAALLLLLL ITVGALVPDI GVQARALLVW KASLSNQSQQ ALMSWENAST
LCSWHGVSCT VHQRRPVISG ISLRGMQLRG TLELLNFTVL TTLTSLDLSH NYLSGGIPPG
IETLEELQSL LLQGNQIRGS VPLDKMSSNL VTLNLSLNHL VGHIPSEIGH LTHLVTLDLS
SNNLSGSIPS NIGGLTKLAT LNLCQNELSG QIPQELGYQV NLEVLDLSEN TLSGSIPDIL
GNLTKLNSLY LWDNKLSGQI PQELGYLVNL EGLSLQKNIL SGSIPRNLCN LTKLTFLRLW
ENILSGQIPQ ELGNLVKLEN LALQDNTLSG SIPITIGNLT NLTLLYLYKN QLSGPIPQGI
VKLLSLVKLD LAFNNLSGAL PFNLCVGGQL QHLSATSNNL VGPLPSSLLS CKSLVRVRLE
RNNLEGDITG MGAYPNLLYI DVSSNKLFGR LSHLWGGCYK LTVLRASNNN ITGVIPSSIG
KLTQLGILDV SSNKLEGQIP REIGNLTMLF NLSLSGNLLQ GNMPQEIGSL NNLEYLDFSS
NNLTGQIPRS IEHCLKIHFL KLSHNHLNGT IPIELGMLVN LQDMLDLSDN SIVGSIPSLL
DDLGMLEALN LSHNALNGSI PPSFRSMTSL LSMDVSYNKL EGLVPHTRFF EEAPIKWFRN
NKKLCGVVKG LPPCDLPRSS KQGKKSGASL LVIIPVVISF VFVITLVITW HCKRKKNKIE
TTNEVQQTMM FAIWNFDGEY VYKKIVDATN NFSKDFCIGS GGNGSVYRAQ LATGELFAVK
KIHVAEDDEQ FNREIHSLMH IRHRNIAKLF GYCSATQGRF LVYEYMGRGS LAASLNCLET
AVEMDWTRRL NIVRDVAHAL SYMHHGCFAP IVHRDIKSSN VLLDLEFKAC ISDSGLAKIL
DVNGSNCTNL AGTKGYLAPE LAYTTKVTEK CDVYSFGVLV LELFMGHHPG DFLSSIVHKT
TLLRNWLDTR LPLPGPEIAS EMFQMIVVAI RCIEPDPSHR PTMQQVLKVL STVERSPADH
LDYLQTGIVI PACWS
//
