ID A0A3B6TR60_WHEAT Unreviewed; 971 AA.
AC A0A3B6TR60;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=USP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_057674 {ECO:0000313|EMBL:KAF7049062.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7D02G280800.3};
RN [1] {ECO:0000313|EMBL:KAF7049062.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7049062.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7D02G280800.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7D02G280800.3};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7D02G280800.3}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7049062.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7049062.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C19 family.
CC {ECO:0000256|ARBA:ARBA00009085}.
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DR EMBL; CM022221; KAF7049062.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6TR60; -.
DR EnsemblPlants; TraesCS7D02G280800.3; TraesCS7D02G280800.3; TraesCS7D02G280800.
DR Gramene; TraesCS7D02G280800.3; TraesCS7D02G280800.3; TraesCS7D02G280800.
DR Gramene; TraesCS7D03G0634800.3; TraesCS7D03G0634800.3.CDS; TraesCS7D03G0634800.
DR Proteomes; UP000019116; Chromosome 7D.
DR Proteomes; UP000815260; Chromosome 4B.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02661; Peptidase_C19E; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF874; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 116..153
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT DOMAIN 463..768
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 201..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..854
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 884..930
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 35..62
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 799..854
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 971 AA; 106684 MW; 8694131A74550F9F CRC64;
MAMAEAAGSS TAATAVTVVL FIVVLVVALL LRQSLRRAAE RREEVRRLAR LAAEESELAE
RESVLAYCSE LFPGVLHAAD VPEAPMWAPR EVVSPQEEEE GVVEAPAPPP AAAGVCAVCF
RPTTFRCKQC KAVKYCSFKC QISHWRKGHK DECHPPSANA KPDDGAAISV AKEGNVEHRR
ASEENVVAGV QPVAEISVPV AAESETSGTN HVVKSSNDKR KDTPFEGVSA TTEIPEKGNS
DNVVKLGQIT PQVASFDSKR AESNTKSTNF VGNSYVKDLD DILVHKSQVS APKMSGLTSS
IHEDIYVHCK DHGNAEDADV SKDCSRINHI RKPADRSYSQ MAATAVPAPK SSRTSLRVEV
EPCKIKATGE EKSQGLKLVT PVLAVDKVSS IHGGRSVAPN PSRRADNPTD RGGSAANNLA
TSLKKIVRQQ TTPKVVRHYP SELTLFPYDV FIKLYDKVEL RPFGLHNLGN SCYANVVLQC
LMFTRPLTTY LLGGLHSKNC SKKAWCFMCE FERLIVEGKQ GKTALSPTGI LSHLHEIGSS
FGPGKQEDAH EFLRHSIDAM QSVCIKEARK GGAHCSAEET TLVQLIFGGY LRSKIKCTRC
HISSEQYERM LDLTVEIDGD ISSLEEALQR FTSTEVLDGD NRYQCSRCNS YERAKKKLTI
SEAPNVLTIA LKRYQSGKFG KISKAIRFPE TLNLSCYMNS TDDNSPVYSL YGMVVHHDVM
NAAFSGHYVC YVKDTHGKWY KIDDSQVKPV SLENVMSKCA YMLFYARCSP RAPNSVRHAM
MVNDPSYAKK AKHKPNLEQT PLQRGSLNRH QGAAESPSPS ESSSLFSNSD AGSHSTVSTD
SSESTRNSTS TDDYEQYFFG SSDQMYLGGP RGAHEEIGYT SYSRSRSALG TSSSGQEVDE
ERSVEQRFEV SRGGWLEGGE SSPLSYTDQS KEHLLTEQYR QFGGSEHDPG EARGSVLLRR
SAREKTAQTF Y
//
