ID A0A3B6TS67_WHEAT Unreviewed; 644 AA.
AC A0A3B6TS67;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=CFC21_109343 {ECO:0000313|EMBL:KAF7109003.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7D02G289800.1};
RN [1] {ECO:0000313|EMBL:KAF7109003.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7109003.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7D02G289800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7D02G289800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7D02G289800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7109003.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7109003.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR EMBL; CM022231; KAF7109003.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6TS67; -.
DR SMR; A0A3B6TS67; -.
DR STRING; 4565.A0A3B6TS67; -.
DR EnsemblPlants; TraesCS7D02G289800.1; TraesCS7D02G289800.1; TraesCS7D02G289800.
DR Gramene; TraesCAD_scaffold_004135_01G000100.1; TraesCAD_scaffold_004135_01G000100.1; TraesCAD_scaffold_004135_01G000100.
DR Gramene; TraesCLE_scaffold_054302_01G000100.1; TraesCLE_scaffold_054302_01G000100.1; TraesCLE_scaffold_054302_01G000100.
DR Gramene; TraesCS7D02G289800.1; TraesCS7D02G289800.1; TraesCS7D02G289800.
DR Gramene; TraesCS7D03G0681000.1; TraesCS7D03G0681000.1.CDS; TraesCS7D03G0681000.
DR Gramene; TraesPAR_scaffold_003504_01G000100.1; TraesPAR_scaffold_003504_01G000100.1; TraesPAR_scaffold_003504_01G000100.
DR Gramene; TraesROB_scaffold_005490_01G000100.1; TraesROB_scaffold_005490_01G000100.1; TraesROB_scaffold_005490_01G000100.
DR Gramene; TraesWEE_scaffold_006125_01G000100.1; TraesWEE_scaffold_006125_01G000100.1; TraesWEE_scaffold_006125_01G000100.
DR OMA; SKTDDRN; -.
DR OrthoDB; 2721872at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000019116; Chromosome 7D.
DR Proteomes; UP000815260; Chromosome 7D.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.20.930.20; Adaptor protein Cbl, N-terminal domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036537; Adaptor_Cbl_N_dom_sf.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23315:SF341; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR PANTHER; PTHR23315; U BOX DOMAIN-CONTAINING; 1.
DR Pfam; PF00514; Arm; 2.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00185; ARM; 4.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50176; ARM_REPEAT; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 273..347
FT /note="U-box"
FT /evidence="ECO:0000259|PROSITE:PS51698"
FT REPEAT 407..449
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 71134 MW; 16A2D772BED67697 CRC64;
MPQPALPPSA AATADPEPSG TPAREMDDED LVEELLATVN SARAYSEFRR TQRKECHNLL
RWLQLILPLL EELRDSAPRL TDDAYRRLTL LGRALSAARR LLRSCNDGSK IFLALESEAV
LGRFRAVYEK MNSALDGMPY AELDISDEVT EQVELMNAQL MRCKKRTDTQ DMELSMDLMV
ILQNNKDEER NADGAIVDRL ASKLELQMLP DLRAETVAIK KLISERNGQH ADSTKQIIEL
LHKFKAIAGI DEKNVLGGEV FVTKSLDKCP SLMIPDDFLC PITLEIMTDP VIVASGQTYE
RRSIQKWLDS GERTCPKTRQ PLAHLSLAPN YALKNLILQW CDKHKVELQR REPEPVAEQD
GHPREDIPSL VEALSSIHPD VQRKAAKKIR MLSKESPENR ALIVGNGGIP ALIGLLAYPD
KKVQENTVTS LLNLSIDHGN KLLITKGGAI PLIIEILRNG SAEGQENSAA TLFSLSMLDE
NKATIGTLGG IAPLVELLTN GTVRGKKDAA TAIFNLILNQ QNKVRATQAG IVPALMKVID
DRSLGMVDEA LSIFLLLSSH PTCLGEIGTT PFVEKLVQLI KEGTPKNKEC ALSVLLELGS
KKQTLLVHAL RFGLHEHLSQ IAKTGTSRAQ RKANSLIQIA KKCY
//
