ID A0A3B6TT20_WHEAT Unreviewed; 3415 AA.
AC A0A3B6TT20;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KAF7109303.1, ECO:0000313|EnsemblPlants:TraesCS7D02G313700.3};
GN ORFNames=CFC21_109589 {ECO:0000313|EMBL:KAF7109303.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCS7D02G313700.3};
RN [1] {ECO:0000313|EMBL:KAF7109303.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7109303.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCS7D02G313700.3}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCS7D02G313700.3};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCS7D02G313700.3}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7109303.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7109303.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
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DR EMBL; CM022231; KAF7109303.1; -; Genomic_DNA.
DR STRING; 4565.A0A3B6TT20; -.
DR PaxDb; 4565-Traes_7DL_8DD408E17-2; -.
DR EnsemblPlants; TraesCS7D02G313700.3; TraesCS7D02G313700.3; TraesCS7D02G313700.
DR Gramene; TraesCS7D02G313700.3; TraesCS7D02G313700.3; TraesCS7D02G313700.
DR Gramene; TraesCS7D03G0746600.3; TraesCS7D03G0746600.3.CDS; TraesCS7D03G0746600.
DR OMA; ECIFRIT; -.
DR Proteomes; UP000019116; Chromosome 7D.
DR Proteomes; UP000815260; Chromosome 7D.
DR GO; GO:0019898; C:extrinsic component of membrane; IBA:GO_Central.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR GO; GO:0045053; P:protein retention in Golgi apparatus; IBA:GO_Central.
DR GO; GO:0006623; P:protein targeting to vacuole; IBA:GO_Central.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF06650; VPS13_VAB; 2.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 2..115
FT /note="Chorein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12624"
FT DOMAIN 137..369
FT /note="Vacuolar protein sorting-associated protein 13
FT extended chorein"
FT /evidence="ECO:0000259|Pfam:PF16908"
FT DOMAIN 2031..2331
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2412..2657
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2973..3147
FT /note="Vacuolar protein sorting-associated protein 13 DH-
FT like"
FT /evidence="ECO:0000259|Pfam:PF16909"
FT DOMAIN 3237..3304
FT /note="Intermembrane lipid transfer protein VPS13 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21679"
FT REGION 418..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3415 AA; 380913 MW; 5DFC443593339FB9 CRC64;
MFEGVVSQVL AGLLGRYVKG IQKEQLKIGI WNEEINLENV ELILEAFDYL QLPFALKTGR
IGKLSIKIPW KKLGWDPIII VIEDVFVCAY PREDSEWGSE SLGKRELAGK LAKLNAIELA
KFSRRVTDNQ TGQSLLSYMS AKILDNIQVS IQNVHIIYVE SHNDQGSFIF GLVFNSLSMQ
TDTQKQSFAM SLMARSRQDE VNKKINISNV GIYCQQLEEQ QNLNDVGALT DAQSNFSLGL
AHPRDDYLIN PFCVTVSVLA NNSGKRDGVP QYDMTAELTA LVLSIDEIQL QQILNLCDHF
TICALRTKYG RYRPPESFLS KRHKGWQIMW WQYAKDSIMA DVKRRLKKTS WRFLGKRLEY
RRKYVNLYRT KLELLQKGQL VSKDILQKLE TLDKECDIDD IVSYRTIAEQ RLQDLSVKST
KDNFSSPGSP RTDEPSAGAG RGWLNWLSLG MLGAGGTADT SSFAGVVSED IIKDIYEGTE
FHPVSSAENH LTKENYYSLR LSIPQILTTV TSRRFGMKLI DGMFTGLGTE YKIWDDSATI
LAWLDSLEIT NPLNKNKVLL AEKCSTGDGL GAPVISIQVD FLKSNENSEA STRVVVQEFN
VIYEPELFFN LLHIYDLFSS FQFQHDRVLS SLNRFDNFGT RLLSKLEYMS VNQKKLLWDL
RIHHFVIKLP SYDCGRELTM VFEAEDISMR SKDRVDDDSQ TQDNNYFLDY MSKKTSTCFS
DSLLPGLQLD DLYNHFEVSL TGFEVKVLMA SRHDITSTLV KLDASIVLGL CIFLDEPMLK
QLEVASIVRS ANIYFSRTMY SAVVNLSTYL KESDLVGSNT SVDTKTNGPN KPALNMSASL
KLDKLSLRVD LEDNGKECSL ITVSVGDIDI RYAVWELSEL WIITKMVEIT STDLKNKSNS
HVLCSSGNYK TSTCVDLTGF PESFAAEACL KLHYRTHKYN DQIHHVYQLN LNDVDLHVHP
SVFGQIKKFL SNLDAVSPGG SAVVSSMDQS SMKPKAANAK FPKLSLADIC GAGSTSFGGV
SVDHFPFLHA DIISNFGCLE TRDVQALDIT PSNGYSAPEL SSNVQCKTEH SNCSSNSLNN
TNNVSTTVLD LSLVSVRTHF HESCGILATL TVPESIATFS LVDATSWDLL LSAKDILLAS
PWTSPSVSEV LWGTYSHGNS NVLNVRVKKD LSALSTEVCI ATQNVCCVLP TKLLAMIIGY
FLLDDWDPMV EEHHSVASNN LECSGELHDS ITYTIEICDC VILFPIENQE LFCIKLGVPY
FFCEFIPTGI SAEFVKHIPK EFFSSECTLS SRVDVISLCS RDASISLVFL NEKTKFIPKL
DEDMPARIHP LVEKLDAGIW IQVPCKTLSC SEQPLLATFI MSKISKCNLI SEDLYFMDGM
ETVFRITDEL TSIVKESKMY EGNARQFLER RRSNEESVES NEPINITISI KDLVVLFGHS
KDKELPLEKV ATANLEFDVS AVMVNEKPEH VDMDIVSLAL HSSGGHTLVS IVSDGPSSPI
LIKFTKHHAG RDEILITVPF FEIWLYLVDW DIIINHFHSC IGKEDNSLHA GHPAASPHFS
GSAMSSFLES ESQDNSYLVV TCESIAVVVH VPIWEKEQNE NSNYPRVDGN SGSYLIHHAD
DTQSNERRGC KFVTLTFESK HFVVMLGESW VKFKCDLDRV KVILEMIQVS KGASVPFMHI
SKIKAGGYIH QSETDMLHLS VDLQAEYMDI SFSHQIFSFW RSIELRFPKS SSSASSFCSV
TLKAGLRKGS LLLNDGRWSS HGPVIETLVK NLSLQFSQMG VETEVSAFVD FLINYNNIDK
VMWEPFIEPS SFQLNILRKC ADHALDVSPI TEVSLNSSKQ LNVNISEPLI EAIFRLSEMI
TDSLNPSSGG DLREDPGIVR LSRDDVHTRR YAPYILSNDT SLPFSFKVYR GAVNSDDIDS
FSIVDENSVP AGYSVPIFVE ETLDEFFFQH REARSSEHLI EKWMSAVSHY MISIEFDGTS
GSSKPMSIDL VGIYFFEVNF SSSKKPILGE ESLEAFGSGR KGSHHDGLIV PVVLDVSLQN
YSKLVRVYST VILFNATSMP LELRFDIPFG VSSKVIGPIL PNKEIPLPVH LSEAGQIRWH
PVGRTYLWSE THSLSSLLSR ESRVGFMKSS VCYPSHPSND PFRCCVSVEE YTVPSSSSAQ
KGQYCTDHLN AQPILGNTAP RASKQVLTRT HFIRQVRLST PLLIKNNLPV CVSLTIDNGG
VAHQVSLKEV GTASIYFVDP SNDLGITFHI QDYRSVTIKF PRVESFSNGA TSNGLKFSLT
ETIAFYSNVS KCPFNVMLEK ATDAHSGARE LCLSVPFLLY NCTDLLLTVT EISYERSGST
LLIPCSFELD GHTRHVLGKN GLSLVSEDPS IQHFASKMPQ LDFIDGRSSH SNRRVANNSE
HVQKECDGEA KAYMFAPAGH TPPTELSVKL NASVPNSGTE TTRRDWSSPF LLVPSSGSTS
LTIPQSSTSS AFLIAVTSVP VSTELFGRTK AIAFQPRYVI CNACSNDMFY KQKGTRFSKH
LSSGQHSFLH WADTARELLV SIRFDGPGWQ WSGSFFPDRL GDAQVKMRNS ASGVSNMVRV
EVQNADIDMH SKKIAGRNNS TTGTILILLS DDKTGFVPYR IDNFSLEKLR IYQQRCESIE
TIVYPYTSCQ YAWDEPCYPH RLIVEVPGER SLGTYSLDVL SDDVHVALPS TPEKAERKFG
ISVHAEGAIK VLSIIDSNCH NMDTKEAGVL GSREPKDADH KQEIELNFTE VIKIHLPFMG
ISLISSSPQE LLFASAKDMT FVAMQSLDQQ RITVEIPSMQ IDNQFSDSPY PVMLSFEGSH
KGKSINFLKS KDTKLKSLNE SRSSNTPEPV LRFAAVKWRT KDTSFLSYQR INISVAPFCL
ELEERLVLSM IDFFRSVSSR VHFGLLEKSV DSSILCGATD IFGEYAKISK NLSDKPQSSY
TVDTDQDNGL LPSVIPIGAP WQQIHLLARK QKKVYIELFE LTPVKLTFSF TSTPWLNRNE
GVSDPSTSFN NSTAIQRGLM ALIDVEGVPV HLGEIMVENL MASWQSIQDI LVRHYSRQLL
HELYKVFGSA GVIGNPMGFA RNVGFGLKDF MSASRKGKLQ SPVELLNGIA QGSKNLIGST
VYAVSSATSH FSKTAYKGLV AFTYDEQTAS KLDERDRQLG LHGEGVLNGF LEGLTGLLQS
PIRGAEKHGL PGVISGIAMG TAGLVARPMA SILEATGRTA QSIRNRSNPH ESNRLRVRFS
RPVARDRPLF PYSWEEAVGV SLLLQADCGR LKDETFVVCK ILREPAKFLV LSEKLLLLVS
SRYLVDLGSP QFAGVPPDPQ WAIETEMNLK SIVHLDRAQE VVNIVGSNGE TSPRDKRGRS
RDIALSSAFI PLFHFSVELP SIEDAEGTLQ FLMALIEKGK ARRWDKNILH RSNIC
//
