ID   A0A3B6TYC2_WHEAT        Unreviewed;       759 AA.
AC   A0A3B6TYC2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=DUF4220 domain-containing protein {ECO:0000259|Pfam:PF13968};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCSU02G004100.1.cds1};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCSU02G004100.1.cds1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCSU02G004100.1.cds1};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCSU02G004100.1.cds1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B6TYC2; -.
DR   STRING; 4565.A0A3B6TYC2; -.
DR   EnsemblPlants; TraesCSU02G004100.1; TraesCSU02G004100.1.cds1; TraesCSU02G004100.
DR   Gramene; TraesCAD_scaffold_062721_01G000100.1; TraesCAD_scaffold_062721_01G000100.1; TraesCAD_scaffold_062721_01G000100.
DR   Gramene; TraesCLE_scaffold_040120_01G000100.1; TraesCLE_scaffold_040120_01G000100.1; TraesCLE_scaffold_040120_01G000100.
DR   Gramene; TraesCSU02G004100.1; TraesCSU02G004100.1.cds1; TraesCSU02G004100.
DR   Gramene; TraesPAR_scaffold_079419_01G000300.1; TraesPAR_scaffold_079419_01G000300.1; TraesPAR_scaffold_079419_01G000300.
DR   Gramene; TraesROB_scaffold_090348_01G000100.1; TraesROB_scaffold_090348_01G000100.1; TraesROB_scaffold_090348_01G000100.
DR   Gramene; TraesWEE_scaffold_113549_01G000100.1; TraesWEE_scaffold_113549_01G000100.1; TraesWEE_scaffold_113549_01G000100.
DR   OMA; MGQASIM; -.
DR   Proteomes; UP000019116; Chromosome Un.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025315; DUF4220.
DR   InterPro; IPR007658; DUF594.
DR   PANTHER; PTHR31325:SF26; DUF4220 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR31325; OS01G0798800 PROTEIN-RELATED; 1.
DR   Pfam; PF13968; DUF4220; 1.
DR   Pfam; PF04578; DUF594; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        47..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        353..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          130..500
FT                   /note="DUF4220"
FT                   /evidence="ECO:0000259|Pfam:PF13968"
SQ   SEQUENCE   759 AA;  85115 MW;  AB7F2C84E332D6AD CRC64;
     MAFFIKHVRW VVLRLNALLV TNAILMAVIA GLGTYGHHYR HHPLIRFLYL GAITLFLPIV
     SDVVSTIQNP YTITVYPKHD RVILSNCEAD GHVFLVILWI GLVQIVGANT ITIVAGDSRE
     GRSIAPPAVQ LVKAIWTSYL AYMMIESGLE PYGYNVKWSQ DRQLSLLDIL LLALPYALIL
     AKLLFKYYAW YKASRSLAFG RNPRLIVGYM EKLQVGTHYA ELTISEHDVP PPLIVMGEDT
     VLVEKQPHGY NLAGMNINNG LLTIDTVWQL DDTLLLWRSK DLCLAFALFK MLRCRFARYT
     INEAGFAKAS NFIRHVLLED SDDERVLGLI TNELSFLHDY YFSYLPVTYS ESWLPFLSVS
     ISLSSIGYCL FVITFLVTTF RGYSALDYEQ IYCHPVHCHP VSDSTYTFTS DSKAEVSFGR
     LLFDVLPVCL LGTLGVLVEA REIASYICSN WTKVALICGY VKHTSWQQSP MIRKCIGHVL
     HTRCKLLDRW EDKMYQCSIL VLHPSRNPIT LLRRILHLPD QKMKVPTAVK AAVLDVVRMN
     QRNKLGNNGA TPRRLQVGSD LLWTFHEAKG AADAMLVCHV ATSILEMTRS REQLPSDHEI
     VATHLSRYCA YLVACCPKLL PDDHVWCRSL YKAVKKDAGR VLAGHDITVS SSEAEHRRLV
     ELLRARSKHQ VLKDGAELGQ RLAELPKGEE VAWKALAGFW TEMIVSVAAT CDNIDEHAEA
     VARGGELVTL LWALLAHVGS VDDDTATAAA ATHGAPDAV
//