ID   A0A3B6U309_WHEAT        Unreviewed;       946 AA.
AC   A0A3B6U309;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblPlants:TraesCSU02G001800.1};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCSU02G001800.1};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCSU02G001800.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCSU02G001800.1};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCSU02G001800.1}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   AlphaFoldDB; A0A3B6U309; -.
DR   SMR; A0A3B6U309; -.
DR   STRING; 4565.A0A3B6U309; -.
DR   EnsemblPlants; TraesCSU02G001800.1; TraesCSU02G001800.1; TraesCSU02G001800.
DR   Gramene; TraesCSU02G001800.1; TraesCSU02G001800.1; TraesCSU02G001800.
DR   Gramene; TraesCSU03G0002800.1; TraesCSU03G0002800.1.CDS; TraesCSU03G0002800.
DR   Gramene; TraesKAR4A01G0487310.1; cds.TraesKAR4A01G0487310.1; TraesKAR4A01G0487310.
DR   Gramene; TraesWEE_scaffold_089636_01G000200.1; TraesWEE_scaffold_089636_01G000200.1; TraesWEE_scaffold_089636_01G000200.
DR   OMA; CNDEEDY; -.
DR   Proteomes; UP000019116; Chromosome Un.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1116; OS11G0657900 PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT   DOMAIN          9..97
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          182..427
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
FT   COILED          21..48
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   946 AA;  107409 MW;  434D87DF91922901 CRC64;
     MAMSMATGAM GSLLPKLVKL LKEEYKLKES VKEGVRSLEE EMKSMQAALR MVGEVPRDQL
     NEHVKIWAAE VRELSFKMED IVDKFFVRVD DGSEPAASPK KLKRLTKKMV GLFTKGKARH
     EISDAIKSIN KKVQEVADRR ARYNVDNIVA RPAAVTPIDP RLGALYKEVT DLVGITGTRD
     KEIIKLLSEG DDVSKKKLKI ISVVGFGGLG KTTLVKTVYD KIKGDFECRA FVPVGRNANA
     KEVFMDILHE LDPQKDKGQL TMLNERQLID KIQLRLENKR YLVVIDDIWD GNLWTVINWA
     FSNNNTLGSR LITTTRKVDV AELCCTSPNG SVYQMKPLSA DDSKRLFYRR LFSHESGCPL
     EFEEVSMDIL KKCGGVPLAI ITIASSLSSG QQVKPKDEWH VLLESIGRGL TEDPSVEEML
     RILSFSYYDL PAYLKTCLLY LSMFPEDHKI MKNQLIWMWI AEGFIQCETT QSSLFEIGEN
     YFNELVNRSL LQPVYVNNMS GHVHACRVHD SVLDLICLLA REENFVSVSN GSISSQGNVR
     RLSLQKIIKE EHETTPLESV SMLQVRSIAT FEPAMGLMYH LSSFVVLRVL NLSTCQLYDH
     NLWGLWSLVH LRYLGLSDTQ LWELPEEVGK LRYLQVLDLS GNLSMKQLPS SITKLRRLMC
     LLYVKTCNRF PDEIGNLTSM EELSCIHVDS LNIVKEMGNL KRLRKFEVEF EHLSLELQEA
     FLKSLGEMSN VQSVTITIDG RYKMMDLFGE KWVPPRGLRE LKSCFGREFR FSRMPAWIRE
     NPSQLAQLSH LFIAVKEVQQ VDLRLLGRLP ALVSLFLKSL RHGPLLIDAD GFRCLTEFTL
     WSSSPGQVMF QSGALPMVDL IIFRTGLPVV GDWVDMGIEN LQSLRLVNVE ICISPMECDY
     EAAHKVYSVL ENALPAHPNS PKYVVRITVN DSDENESKGG DDDEWE
//