ID   A0A3B6U4Q6_WHEAT        Unreviewed;       974 AA.
AC   A0A3B6U4Q6;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=NAD kinase 2, chloroplastic {ECO:0008006|Google:ProtNLM};
OS   Triticum aestivum (Wheat).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX   NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCSU02G067800.2};
RN   [1] {ECO:0000313|EnsemblPlants:TraesCSU02G067800.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Chinese Spring
RC   {ECO:0000313|EnsemblPlants:TraesCSU02G067800.2};
RX   PubMed=30115783; DOI=10.1126/science.aar7191;
RG   International wheat genome sequencing consortium (IWGSC);
RT   "Shifting the limits in wheat research and breeding using a fully annotated
RT   reference genome.";
RL   Science 361:EAAR7191-EAAR7191(2018).
RN   [2] {ECO:0000313|EnsemblPlants:TraesCSU02G067800.2}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (OCT-2018) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NAD kinase family.
CC       {ECO:0000256|ARBA:ARBA00010995}.
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DR   AlphaFoldDB; A0A3B6U4Q6; -.
DR   EnsemblPlants; TraesCSU02G067800.2; TraesCSU02G067800.2; TraesCSU02G067800.
DR   Gramene; TraesCSU02G067800.2; TraesCSU02G067800.2; TraesCSU02G067800.
DR   Gramene; TraesKAR4B01G0070030.1; cds.TraesKAR4B01G0070030.1; TraesKAR4B01G0070030.
DR   OrthoDB; 455155at2759; -.
DR   Proteomes; UP000019116; Chromosome Un.
DR   GO; GO:0003951; F:NAD+ kinase activity; IEA:InterPro.
DR   GO; GO:0019674; P:NAD metabolic process; IEA:InterPro.
DR   GO; GO:0006741; P:NADP biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR   HAMAP; MF_00361; NAD_kinase; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   InterPro; IPR002504; NADK.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   PANTHER; PTHR20275; NAD KINASE; 1.
DR   PANTHER; PTHR20275:SF0; NAD KINASE; 1.
DR   Pfam; PF01513; NAD_kinase; 1.
DR   Pfam; PF20143; NAD_kinase_C; 1.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   NAD {ECO:0000256|ARBA:ARBA00023027}; NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   REGION          375..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          543..603
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        382..399
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        419..438
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        543..592
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   974 AA;  107594 MW;  23DC1C03A4499ECF CRC64;
     MLAVCARHGP AQLPLPPLGG ERVAWVAAGR WWCWRPAAAR RGVAARASSF NSRIGLDSQN
     SHTRDLSQLL WVGPVPGDIA EIEAYCRIFR AAEQLQNAVM SALCDPETGE CPVRYDVPSE
     DLPVLEDKVA AVLGCMLALL NRGRTEVLAG RSGVTSAFQG SEHSTMDRIP PLALFRGDMK
     RCCESMQVAL ASYLVPSEPR GLDIWMRLQR LKNACYDAGF ARVDGHPCPT LFANWFPVYF
     STVPDDSETD ELEVAFWRGG QVSEEGLAWL LAKGFRTIVD LREEDVKDDL YLSAVGKAVS
     SGKIEVVNMP VEIGTSPSAE QVQQFAALVS DGTKKPIYLH SKEGINRTSA MVSRWKQYAT
     RAERLATKKR SPIVNGKALK NDPTNGLGSL SNGSENGAVV KSDRTMDAGE ARDIDIEITS
     NNPEVTNSLP NGQSTEQGEM HDSRTELLSD FKLETSPLKA QFPTCNVFSR KEMTKFFRSK
     RVYPKSVLNS RRRSSSLMIS RRKQNLRAEH NEAIDCEAAD MMVLKNANGT LFDNDYILSV
     SSGITNRKPS NNGTSTSFEE KGSAASLLTI DPKTSNASNP NGNAQLGSQK PSEKNGGPYL
     ERYSSDTIDG SICATTGVVR VQSRRKAEMF LVRTDGFSCT REKVTESSLA FTHPSTQQQM
     LMWKSPPKTV LLLKKLGDEL MEEAKEVASF LYHQEKMNVL VEPDVHDIFA RIPGYGFVQT
     FYTQDTSDLH ERVDFVTCLG GDGVILHASN LFRTSVPPVV SFNLGSLGFL TSHNFEGFRQ
     DMRAVIHGNN TLGVYITLRM RLRCIIFRNG KAMPGKVFDV LNEVVVDRGS NPYLSKIECY
     EHNHLITKVQ GDGVIVATPT GSTAYSTAAG GSMVHPNVPC MLFTPICPHS LSFRPVILPD
     SARLELKIPD DARSNAWVSF DGKRRQQLSR GDSVHISMSE HPLPTVNKSD QTGDWFRSLI
     RCLNWNERLD QKAL
//