ID A0A3B6U516_WHEAT Unreviewed; 426 AA.
AC A0A3B6U516;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN ORFNames=CFC21_057384 {ECO:0000313|EMBL:KAF7048671.1}, CFC21_057448
GN {ECO:0000313|EMBL:KAF7048754.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCSU02G068800.4};
RN [1] {ECO:0000313|EMBL:KAF7048671.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7048671.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCSU02G068800.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCSU02G068800.4};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCSU02G068800.4}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7048671.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7048671.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:83421; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001512};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001482};
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DR EMBL; CM022221; KAF7048671.1; -; Genomic_DNA.
DR EMBL; CM022221; KAF7048754.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6U516; -.
DR EnsemblPlants; TraesCSU02G068800.4; TraesCSU02G068800.4; TraesCSU02G068800.
DR Gramene; TraesCSU02G068800.4; TraesCSU02G068800.4; TraesCSU02G068800.
DR Gramene; TraesCSU03G0070200.3; TraesCSU03G0070200.3.CDS; TraesCSU03G0070200.
DR Proteomes; UP000019116; Chromosome Un.
DR Proteomes; UP000815260; Chromosome 4B.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd00143; PP2Cc; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR015655; PP2C.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR47992:SF191; PROTEIN PHOSPHATASE 2C 12-RELATED; 1.
DR Pfam; PF00481; PP2C; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR PROSITE; PS51746; PPM_2; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 33..300
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
SQ SEQUENCE 426 AA; 45737 MW; 26E26DB6D91576CB CRC64;
MEVHNEVDGS GVPLAVLLKR ELCNQKVEKP DILFGEASKS KKGEDFTLLV ANCHRTPGEG
PGDNAGGDDT ISMFVIVDGH NGPAAAVYTR ENLPNNVLAA IPPNLTSEEW TAALPRALVA
GFVKTDKDFQ TKAARSGTTV TFVIIDGWVV TVASVGDSRC ILESAEGSVY FLSADHRLDV
NEEEVERVTA SGGEVGRINI AGGAGIGPLR CWPGGLCLSR SIGDTDVGEY IVPVPHVKQL
SNAGGRLVIA SDGVWDALHF QEALNYTRGL PAEAAANRIV KEAVSSKGLR DDTTCIVVDI
LPPEKLSPPL KRHGKGGIKA LFRWRPSDEL SEEQTDNGCF EPDVVEELYE EGSAMLAQRL
NVNYPAGNMF KLHDCAVCQL EMKPGEGVSV HGNMPKHHSR VDPWGGPFLC SSCQVKKVAM
EGRLHL
//
