ID A0A3B6U539_WHEAT Unreviewed; 926 AA.
AC A0A3B6U539;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CFC21_085591 {ECO:0000313|EMBL:KAF7081673.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCSU02G071100.1};
RN [1] {ECO:0000313|EMBL:KAF7081673.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7081673.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCSU02G071100.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCSU02G071100.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCSU02G071100.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:KAF7081673.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:KAF7081673.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM022226; KAF7081673.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6U539; -.
DR SMR; A0A3B6U539; -.
DR STRING; 4565.A0A3B6U539; -.
DR PaxDb; 4565-Traes_6AL_8BF77066D-3; -.
DR EnsemblPlants; TraesCSU02G071100.1; TraesCSU02G071100.1; TraesCSU02G071100.
DR Gramene; TraesCSU02G071100.1; TraesCSU02G071100.1; TraesCSU02G071100.
DR OrthoDB; 338594at2759; -.
DR Proteomes; UP000019116; Chromosome Un.
DR Proteomes; UP000815260; Chromosome 6A.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF1107; OS08G0373000 PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116}.
FT DOMAIN 17..99
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 188..424
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 926 AA; 104230 MW; A1E5A7DC5751E787 CRC64;
MAMEATLVSV ATGVLIPVLG KLSTLLGNEY KRFKGVRKEI RSLTHELGAM EAFLLKMSEE
EDPDSRDKVW MNEVRELSYD MEDAIDDFMQ SVDDKDEKPN GFIEKIKNSL GKLGKMKARR
RIGKEIQDLK KQIVEVGDRN ARYKSREPFS KTVNATIDPR ALAIFEHASN LVGIDEPKAE
IIKLLIEEVV RASEQQQQLK IVSIVGSGGM GKTTLANQVY QELKGKYECW AFVSVSRNPD
MMNILRTILS EVAKKDYATT ESGDIQQLII KIIDFLANKR YFVVVDDIWD MDTWDIIKCA
FPARSSTSRI ITTTRMNSVA NLCCSSFNGH IYNIRALDMV HSRQLFHIRL FKSDEDCPAH
LQEISEQILE KCDGLPLAII AISGLLANTE RTENIWNQVK DSIGRALERN PNVEGMMKIL
SLSYFDLPAH LKTCLLYLSM YLEDSTVEKK GLIRRWIVEG FILGEGRYTA YELGERCFNE
LLNRGLIQPV ETDDYGEVNS CRVHDTILDF IISKSIEENF ITLRGVPILT IGNQSKVVRR
LCLQGVKEGN STVLTEGLVL SHVRSLTVVR GLVKIFSFEE FRHLRVLHLM GCSELDDHHL
ENIMRLFQLR YLNLQGTGIS KLPEQIGRLV CLEILNLTRT YVRGLPASIV NLGKLLHLRV
DHDVKFPNGI AKMQALETLG YVKVSIQPID FVCGLGQLKN LRNLQLDLTF EGDCDIEDRD
VVGEERKKAI VSSLCKLGTQ NLRSLSIWCG SSLLQGPLCL PTLEKLTTGS SAVPQIPTWL
SSSRNLQLLW IEVEVVKQDD LCILGALPSL LVLHLEEAAK SKEKLRISGE VGFQLLRIFI
YDASDEPVDL IFGVGSMPKL EKLELRYLCA VEADCLDFGI GNLPCLSIIK FIGVGGDYDI
VEAVKIAMKR AASAHLNHPS LHFLEE
//
