ID A0A3B6UAZ7_WHEAT Unreviewed; 923 AA.
AC A0A3B6UAZ7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=CFC21_112392 {ECO:0000313|EMBL:MBC2899562.1};
OS Triticum aestivum (Wheat).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4565 {ECO:0000313|EnsemblPlants:TraesCSU02G108800.1};
RN [1] {ECO:0000313|EMBL:MBC2899562.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:MBC2899562.1};
RX PubMed=29069494;
RA Zimin A.V., Puiu D., Hall R., Kingan S., Clavijo B.J., Salzberg S.L.;
RT "The first near-complete assembly of the hexaploid bread wheat genome,
RT Triticum aestivum.";
RL Gigascience 6:1-7(2017).
RN [2] {ECO:0000313|EnsemblPlants:TraesCSU02G108800.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Chinese Spring
RC {ECO:0000313|EnsemblPlants:TraesCSU02G108800.1};
RX PubMed=30115783; DOI=10.1126/science.aar7191;
RG International wheat genome sequencing consortium (IWGSC);
RT "Shifting the limits in wheat research and breeding using a fully annotated
RT reference genome.";
RL Science 361:EAAR7191-EAAR7191(2018).
RN [3] {ECO:0000313|EnsemblPlants:TraesCSU02G108800.1}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (OCT-2018) to UniProtKB.
RN [4] {ECO:0000313|EMBL:MBC2899562.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaf {ECO:0000313|EMBL:MBC2899562.1};
RA Zimin A.V., Puiu D., Shumante A., Alonge M., Salzberg S.L.;
RT "The second near-complete assembly of the hexaploid bread wheat (Triticum
RT aestivum) genome.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; NMPL03045935; MBC2899562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B6UAZ7; -.
DR SMR; A0A3B6UAZ7; -.
DR STRING; 4565.A0A3B6UAZ7; -.
DR EnsemblPlants; TraesCSU02G108800.1; TraesCSU02G108800.1; TraesCSU02G108800.
DR Gramene; TraesCAD_scaffold_000772_01G000500.1; TraesCAD_scaffold_000772_01G000500.1; TraesCAD_scaffold_000772_01G000500.
DR Gramene; TraesCLE_scaffold_008862_01G000100.1; TraesCLE_scaffold_008862_01G000100.1; TraesCLE_scaffold_008862_01G000100.
DR Gramene; TraesCSU02G108800.1; TraesCSU02G108800.1; TraesCSU02G108800.
DR Gramene; TraesKAR6D01G0020870.1; cds.TraesKAR6D01G0020870.1; TraesKAR6D01G0020870.
DR Gramene; TraesPAR_scaffold_035919_01G000500.1; TraesPAR_scaffold_035919_01G000500.1; TraesPAR_scaffold_035919_01G000500.
DR Gramene; TraesROB_scaffold_060596_01G000300.1; TraesROB_scaffold_060596_01G000300.1; TraesROB_scaffold_060596_01G000300.
DR Gramene; TraesWEE_scaffold_020064_01G000700.1; TraesWEE_scaffold_020064_01G000700.1; TraesWEE_scaffold_020064_01G000700.
DR OMA; YQMDAVA; -.
DR OrthoDB; 1011589at2759; -.
DR Proteomes; UP000019116; Chromosome Un.
DR Proteomes; UP000815260; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF587; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000019116};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..923
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039995951"
FT TRANSMEM 590..610
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 833..856
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 471..812
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 879..923
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 761..815
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 923 AA; 102219 MW; 608CF6C8880D9D4C CRC64;
MGIAFPMVLV LSLLLYTNGI SKSLAARPPV VNIGSILQLN STTGGVAAIA INAALEDINS
DPTVLNGTTL KVETKDTNCF DGFLGMVQAL QFMETDVIAI VGPQCSAIAH IISYVANELR
VPLMSFASDA TLSSIQFPFF VRTAPSDLYQ MAAVAAVVDY NHWKIVTAIY VDDDYGRNGI
AALDDALTAK RCKISYKIGF PANAKKSELI NLLVSVSYME SRVIILHTGA EPGLKLFSMA
NRLNMMGNGY VWIATDWLSA YLDANSSVPA ETISGMQGVL TLRPHIPNSK MKSNLISKWS
RQSQKYNHSD LRVNTYGFYV YDSVWTVARA LDAFFDDGGS ISFSNDSRLR DATGGTLHLE
AMSIFDKGRK LLEKIRKVNF TGPSGHVQFD ASGDLIHPAY EIINVIGNGM RTIGFWSNYS
GLLSTVPPEA LYSKPPNTSL ANQQLYDVIW PGETAQRPRG WVFPSNAKEL KIGIPNRFSF
REFVTKDNVT GSMKGYCIDV FTQALALLPY PVTYKFVPFG SGTENPHYDK LIEMVESNEL
DGAVGDIAVT MKRTVNADFT QPFIETGLVI LAPVKRHITT SWAFLQPFTL EMWCVTGLFF
LVVGVVVWVL EHRINDEFRG SPRQQMITIF WFSFSTLFFA HRENTMSTLG RGVLIIWLFV
VLIIQSSYTA SLTSILTVQQ LDTSIKGIDD LKNSDAPVGF QVGSFAQDYM VNELNISRSR
LRALGSPKEY AKALELGPKK GGVMAIVDER PYVELFLSTY CKIAVAGSDF TSRGWGFAFP
RDSPLQVDLS TAILSLSENG ELQRIHDKWL KTGECAADES EMINSNQLRL ESFWGLFLIC
GVACVISLLI YFGIMLRKYM RHEPKKSLRR FISFVDDKEP PKNRKKRSMS LPASSTATAP
MTALDVERPA RPVRNGSVID IEG
//
